Western Blot (WB)
(DGCR14 Antibody (Center) (MBS9206566) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DGCR14 antibody detected the DGCR14 protein (arrow).)
Rabbit anti-Human DGCR14 Polyclonal Antibody | anti-DGCR14 antibody
DGCR14 Antibody (Center)
Western Blot (WB)
(DGCR14 Antibody (Center) (MBS9206566) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DGCR14 antibody detected the DGCR14 protein (arrow).)
Western Blot (WB)
(DGCR14 Antibody (Center) (MBS9206566) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DGCR14 antibody detected the DGCR14 protein (arrow).)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Wang, H., et al. J Neural Transm 113(10):1551-1561(2006)
Jurica, M.S., et al. RNA 8(4):426-439(2002)
NCBI and Uniprot Product Information
NCBI Description
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. [provided by RefSeq, Jul 2008]
Uniprot Description
DGCR14: involved in pre-mRNA splicing. One of the many proteins in the spliceosome C complex. Defects in this gene play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS).
Protein type: RNA splicing; Spliceosome; RNA processing; RNA-binding
Chromosomal Location of Human Ortholog: 22q11.21|22q11.2
Cellular Component: nucleus
Molecular Function: protein binding
Biological Process: nuclear mRNA splicing, via spliceosome; nervous system development
Disease: Velocardiofacial Syndrome
Research Articles on DGCR14
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Product Notes
The DGCR14 dgcr14 (Catalog #AAA9206566) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DGCR14 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DGCR14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the DGCR14 dgcr14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DGCR14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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