Testing Data #1
(Formlin fixed, paraffin embedded normal human kidney stained with Rabbit anti Human defensin β1 (MBS224033) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))
Rabbit DEFENSIN BETA 1 Polyclonal Antibody | anti-DEFB1 antibody
RABBIT ANTI HUMAN DEFENSIN BETA 1
Purified IgG - lyophilised
ELISA: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml
Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Western Blotting: Minimum Dilution: 0.1; Maximum Dilution: 0.2ug/ml
Shelf Life: 12 months from date of reconstitution.
Testing Data #1
(Formlin fixed, paraffin embedded normal human kidney stained with Rabbit anti Human defensin β1 (MBS224033) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))
Testing Data #1
(Formlin fixed, paraffin embedded normal human kidney stained with Rabbit anti Human defensin β1 (MBS224033) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))
Testing Data #2
(Formlin fixed, paraffin embedded normal human kidney stained with Rabbit anti Human defensin β1 (MBS224033) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))
Testing Data #2
(Formlin fixed, paraffin embedded normal human kidney stained with Rabbit anti Human defensin β1 (MBS224033) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))
NCBI and Uniprot Product Information
NCBI Description
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
Uniprot Description
defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: extracellular space; Golgi lumen; extracellular region
Biological Process: G-protein coupled receptor protein signaling pathway; defense response to Gram-positive bacterium; innate immune response in mucosa; response to bacterium; antibacterial humoral response; innate immune response; immune response; response to testosterone stimulus; chemotaxis; acute inflammatory response
Research Articles on DEFB1
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Product Notes
The DEFB1 defb1 (Catalog #AAA224033) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DEFENSIN BETA 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB). ELISA: This purified human defensinbeta-1 antibody may be used in an indirect ELISA or as the capture reagent in a sandwich ELISA with our biotinylated human defensinbeta-1 antibody as the detection reagent and recombinant human defensinbeta-1 as the standard. ELISA: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml Immunohistology - Paraffin: Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Western Blotting: Minimum Dilution: 0.1; Maximum Dilution: 0.2ug/ml. Researchers should empirically determine the suitability of the DEFB1 defb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DEFENSIN BETA 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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