Western Blot (WB)
(Western Blot: Sample: Rat Serum; Primary Ab: 1ug/ml Rabbit Anti-Rat CORO1A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Rat Coronin 1A Polyclonal Antibody | anti-CORO1A antibody
Polyclonal Antibody to Coronin 1A (CORO1A)
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Rat Serum; Primary Ab: 1ug/ml Rabbit Anti-Rat CORO1A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Rat Serum; Primary Ab: 1ug/ml Rabbit Anti-Rat CORO1A Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded spleen tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded spleen tissue))
NCBI and Uniprot Product Information
NCBI Description
actin binding protein; human homolog may be a component of the cytoskeleton and may be involved in mitosis [RGD, Feb 2006]
Uniprot Description
coronin 1A: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q36
Cellular Component: actin cytoskeleton; actin filament; axon; cell leading edge; cortical actin cytoskeleton; cytoplasm; cytosol; early endosome; immunological synapse; intercellular junction; lamellipodium; membrane; nucleus; phagocytic cup; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; protein complex; stereocilium bundle tip
Molecular Function: actin binding; actin filament binding; actin monomer binding; cytoskeletal protein binding; identical protein binding; myosin heavy chain binding; phosphoinositide 3-kinase binding; protein C-terminus binding; protein homodimerization activity; RNA binding
Biological Process: actin cytoskeleton organization; actin filament organization; calcium ion transport; cell migration; cell-substrate adhesion; formation of immunological synapse; homeostasis of number of cells within a tissue; leukocyte chemotaxis; natural killer cell degranulation; negative regulation of actin nucleation; negative regulation of neuron apoptosis; negative regulation of vesicle fusion; phagocytosis; phagolysosome formation; positive chemotaxis; positive regulation of cell migration; positive regulation of T cell activation; positive regulation of T cell proliferation; regulation of actin cytoskeleton organization; regulation of actin filament polymerization; regulation of actin polymerization and/or depolymerization; regulation of cell shape; regulation of release of sequestered calcium ion into cytosol; response to cytokine; T cell differentiation; T cell homeostasis; uropod organization
Research Articles on CORO1A
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Product Notes
The CORO1A coro1a (Catalog #AAA2027537) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Coronin 1A (CORO1A) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Coronin 1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the CORO1A coro1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Coronin 1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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