Rat Coronin-1A ELISA Kit | Coro1a elisa kit

Rat Coronin-1A ELISA Kit

Cat. Num. AAA289455

• Reactivity: Rat
• Synonyms: Coronin-1A; Rat Coronin-1A ELISA Kit; Coronin-like protein A; Clipin-A; Tryptophan aspartate-containing coat protein; TACO; Coro1a; Coro1; Coro1a elisa kit

• Reactivity: Rat
• Sequence Length: 461

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.087 ng/mL
• Intra-Assay CV: <=4.4%
• Inter-Assay CV: <=7.9%
• Recovery: 87%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 18426834
• NCBI GeneID: 155151
• NCBI Accession #: NP_569095.1
• NCBI GenBank Nucleotide #: NM_130411.2
• UniProt Accession #: Q91ZN1
• Molecular Weight: 51,065 Da
• NCBI Official Full Name: coronin-1A
• NCBI Official Synonym Full Names: coronin 1A
• NCBI Official Symbol: Coro1a
• NCBI Protein Information: coronin-1A
• UniProt Protein Name: Coronin-1A
• Protein Family: Coronin
• UniProt Gene Name: Coro1a
• UniProt Synonym Gene Names: Coro1; Clipin-A; TACO
• UniProt Entry Name: COR1A_RAT

NCBI Description

actin binding protein; human homolog may be a component of the cytoskeleton and may be involved in mitosis [RGD, Feb 2006]

Uniprot Description

coronin 1A: May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria- infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes. Belongs to the WD repeat coronin family.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Cellular Component: actin cytoskeleton; actin filament; axon; cortical actin cytoskeleton; cytoplasm; early endosome; immunological synapse; intercellular junction; lamellipodium; leading edge; membrane; nucleus; phagocytic cup; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; protein complex

Molecular Function: actin binding; actin filament binding; actin monomer binding; cytoskeletal protein binding; identical protein binding; myosin heavy chain binding; phosphoinositide 3-kinase binding; protein C-terminus binding; protein homodimerization activity

Biological Process: actin cytoskeleton organization and biogenesis; actin filament organization; calcium ion transport; cell migration; cell-substrate adhesion; formation of immunological synapse; homeostasis of number of cells within a tissue; leukocyte chemotaxis; natural killer cell degranulation; negative regulation of actin nucleation; negative regulation of neuron apoptosis; negative regulation of vesicle fusion; phagocytosis; phagolysosome formation; positive chemotaxis; positive regulation of cell migration; positive regulation of T cell activation; positive regulation of T cell proliferation; regulation of actin cytoskeleton organization and biogenesis; regulation of actin filament polymerization; regulation of actin polymerization and/or depolymerization; regulation of cell shape; regulation of release of sequestered calcium ion into cytosol; response to cytokine stimulus; T cell differentiation; T cell homeostasis; uropod organization and biogenesis