Western Blot (WB)
(Western Blot: Sample: Human Jurkat cell lysate; Primary Ab: 5ug/ml Rabbit Anti-Mouse CD6 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Mouse Cluster Of Differentiation 6 Polyclonal Antibody | anti-CD6 antibody
Polyclonal Antibody to Cluster Of Differentiation 6 (CD6)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- G TIPNMTLDLE ERLGIRLVNG SSRCSGSVKV LLESWEPVCA AHWNRAATEA VCKALNCGDS GKVTYLMPPT SELPPGATSG NTSSAGNTTW ARAPTERCRG ANWQFCKVQD QECSSDRRLV WVTCAENQAV
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Human Jurkat cell lysate; Primary Ab: 5ug/ml Rabbit Anti-Mouse CD6 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Human Jurkat cell lysate; Primary Ab: 5ug/ml Rabbit Anti-Mouse CD6 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Spleen tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Spleen tissue))
NCBI and Uniprot Product Information
Uniprot Description
CD6: a type I membrane protein involved in cell adhesion. Binds to CD166. Expressed on thymocytes, peripheral T cells, a subset of B cells, and a subset of neurons. Mediates the binding of developing thymocytes with thymic epithelial cells. CD6- T cells are less autoreactive than CD6+ T cells. Phosphorylated on tyrosines and serines following T cell antigen receptor signaling. Five splice-variant isoforms have been described.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19 A|19 7.16 cM
Cellular Component: immunological synapse; integral component of membrane; intrinsic component of plasma membrane; membrane; plasma membrane; spanning component of plasma membrane; T cell receptor complex
Molecular Function: identical protein binding; lipopolysaccharide binding; protein binding; protein kinase binding; scavenger receptor activity
Biological Process: acute inflammatory response to antigenic stimulus; cell adhesion; formation of immunological synapse; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; lipopolysaccharide-mediated signaling pathway; positive regulation of cytokine production involved in inflammatory response; positive regulation of protein phosphorylation; positive regulation of T cell proliferation; response to lipopolysaccharide
Research Articles on CD6
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Product Notes
The CD6 cd6 (Catalog #AAA2026446) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Cluster Of Differentiation 6 (CD6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cluster Of Differentiation 6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the CD6 cd6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- G TIPNMTLDLE ERLGIRLVNG SSRCSGSVKV LLESWEPVCA AHWNRAATEA VCKALNCGDS GKVTYLMPPT SELPPGATSG NTSSAGNTTW ARAPTERCRG ANWQFCKVQD QECSSDRRLV WVTCAENQAV. It is sometimes possible for the material contained within the vial of "Cluster Of Differentiation 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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