Structure
NNC 55-0396 Biochemical
NNC 55-0396
Purity
>98% (HPLC)
Synonyms
NNC 55-0396; NNC 55-0396 dihydrochloride; NNC 55-0396 biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO
Target
Calcium Channel
Receptor
Calcium Channel
Chemical Name
Cyclopropanecarboxylic acid, (1S, 2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1, 2, 3, 4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, hydrochloride(1:2)
SMILES
CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl
Molecular Formula
C30H40Cl2FN3O2
CAS Number
357400-13-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for NNC 55-0396 biochemical
A potent and selective T-type calcium channel antagonist that blocks recombinant alpha (1)G T-type channels in human embryonic kidney 293 cellswith IC50 of 7uM; has no detectable effect on high-voltage-activated channels in INS-1 cells; inhibits MCF-7 (ERalpha+) cellular proliferation, inhibits tumor-induced angiogenesis in vitro and in vivo by suppressing HIF-1alpha stability; significantly suppresses glioblastoma tumor growth in a xenograft model.
Product Categories/Family for NNC 55-0396 biochemical
References
1. Huang L, et al. J Pharmacol Exp Ther. 2004 Apr; 309 (1):193-9.
2. Taylor JT, et al. Cancer Lett. 2008 Aug 18; 267 (1):116-24.
3. Kim KH, et al. J Mol Med (Berl). 2015 May; 93 (5):499-509.
2. Taylor JT, et al. Cancer Lett. 2008 Aug 18; 267 (1):116-24.
3. Kim KH, et al. J Mol Med (Berl). 2015 May; 93 (5):499-509.
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Product Notes
The NNC 55-0396 (Catalog #AAA3604226) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NNC 55-0396, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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