Western Blot (WB)
(Western blot analysis of extracts from various samples, using Claudin 17 Antibody.Lane 1: MCF7, treated with blocking peptide;Lane 2: MCF7;Lane 3: Mouse testis.)
Rabbit anti-Human, Mouse Claudin 17 Polyclonal Antibody | anti-CLDN17 antibody
Claudin 17 Antibody
ELISA(peptide): 1:20,000-1:40,000
Western Blot (WB)
(Western blot analysis of extracts from various samples, using Claudin 17 Antibody.Lane 1: MCF7, treated with blocking peptide;Lane 2: MCF7;Lane 3: Mouse testis.)
Western Blot (WB)
(Western blot analysis of extracts from various samples, using Claudin 17 Antibody.Lane 1: MCF7, treated with blocking peptide;Lane 2: MCF7;Lane 3: Mouse testis.)
Western Blot (WB)
(Western blot analysis of extracts from Jurkat, using Claudin 17 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from Jurkat, using Claudin 17 Antibody. The lane on the left was treated with blocking peptide.)
Subcellular Location: Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Tissue Specificity: In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).
Subunit Structure: Interacts with OCLN (PubMed:20375010).
Similarity: Belongs to the claudin family.
NCBI and Uniprot Product Information
Predicted Molecular Weight: (Calculated)25kDa.
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010]
Uniprot Description
Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability.
Research Articles on CLDN17
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Product Notes
The CLDN17 cldn17 (Catalog #AAA9612510) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Claudin 17 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). WB: 1:500-1:2000 ELISA(peptide): 1:20,000-1:40,000. Researchers should empirically determine the suitability of the CLDN17 cldn17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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