Immunohistochemistry (IHC)
(Human Testis, Sertoli Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human Claudin 11 Polyclonal Antibody | anti-CLDN11 antibody
Claudin 11, CT (OSP, Oligodendrocyte Specific protein, CLDN11, OSP, OTM)
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Claudin 11; Polyclonal Antibody; CT (OSP; Oligodendrocyte Specific protein; CLDN11; OSP; OTM); Anti -Claudin 11; anti-CLDN11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CLDN11. Species sequence homology: mouse.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 10mM PBS, pH 7.4, BSA, sodium azide.
Applicable Applications for anti-CLDN11 antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:50
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:50
Immunogen
Synthetic peptide corresponding to C-terminal of human claudin 11.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunohistochemistry (IHC)
(Human Testis, Sertoli Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Testis, Sertoli Cells: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CLDN11 antibody
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans- membrane domains and two extracellular loops, make up tight junction strands. Claudin-11 is an oligodendrocyte-specific protein that is expressed in the tight junctions of Sertoli cells and myelin sheaths in mice.
Product Categories/Family for anti-CLDN11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,012 Da
NCBI Official Full Name
Claudin 11
NCBI Official Synonym Full Names
claudin 11<
NCBI Official Symbol
CLDN11
NCBI Protein Information
claudin-11; claudin 11 (oligodendrocyte transmembrane protein)
UniProt Protein Name
Claudin-11
Protein Family
UniProt Gene Name
CLDN11
UniProt Entry Name
CLD11_BOVIN
Uniprot Description
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
By similarity.
Subunit structure: Interacts with tetraspanin-3/TSPAN3
By similarity.
Subcellular location: Cell junction › tight junction
By similarity. Cell membrane; Multi-pass membrane protein
By similarity.
Sequence similarities: Belongs to the claudin family.
Similar Products
Product Notes
The CLDN11 cldn11 (Catalog #AAA6011292) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Claudin 11, CT (OSP, Oligodendrocyte Specific protein, CLDN11, OSP, OTM) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 11 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 1:50. Researchers should empirically determine the suitability of the CLDN11 cldn11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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