Testing Data
Rabbit Claudin 10 Antibody | anti-Claudin 10 antibody
Rabbit anti Claudin 10 antibody
Gene Names
CLDN10; OSP-L; CPETRL3
Reactivity
Human, Rat, Mouse
Applications
Immunohistochemistry
Purity
The rabbit antibody is purified by affinity purification.
Synonyms
Claudin 10; Rabbit anti Claudin 10 antibody; Rabbit anti-Claudin 10; anti-Claudin 10 antibody
Host
Rabbit
Reactivity
Human, Rat, Mouse
Specificity
This antibody reacts with human,rat and mouse. Others not tested.
Purity/Purification
The rabbit antibody is purified by affinity purification.
Form/Format
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Concentration
Size: 100 ug/200 ul (varies by lot)
Applicable Applications for anti-Claudin 10 antibody
Immunohistology
Application Notes
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 1-2 ug/ml
Immunohistochemistry: 1-2 ug/ml
Antigen Preparation
A synthetic peptide from C-terminus of human claudin 10 protein.
Positive Control
Brain and Skeletal muscle
Cellular Location
Cellular junction/gap
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Testing Data
Testing Data
Related Product Information for anti-Claudin 10 antibody
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands.
References
Hashizume A; Ueno T; Furuse M; Tsukita S; Nakanishi Y; Hieda Y (2004), Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn 231 (2), 425-431.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21 kDa
NCBI Official Full Name
claudin-10 isoform a_i1
NCBI Official Synonym Full Names
claudin 10
NCBI Official Symbol
CLDN10
NCBI Official Synonym Symbols
OSP-L; CPETRL3
NCBI Protein Information
claudin-10; OSP-like protein; OTTHUMP00000018561; OTTHUMP00000018562
UniProt Protein Name
Claudin-10
UniProt Gene Name
CLDN10
UniProt Entry Name
CLD10_HUMAN
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
Uniprot Description
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity
Subcellular location: Cell junction › tight junction. Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the claudin family.
Research Articles on Claudin 10
Similar Products
Product Notes
The Claudin 10 cldn10 (Catalog #AAA462245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Claudin 10 antibody reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Claudin 10 can be used in a range of immunoassay formats including, but not limited to, Immunohistology. Immunoprecipitation: 2-5 ug/ml Immunohistochemistry: 1-2 ug/ml. Researchers should empirically determine the suitability of the Claudin 10 cldn10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Claudin 10, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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