Goat CEBPG / CEBP Gamma Polyclonal Antibody | anti-CEBPG antibody

Goat Polyclonal to Human CEBPG / CEBP Gamma

Cat. Num. AAA247423

• Gene Names: CEBPG; GPE1BP; IG/EBP-1
• Reactivity: Gorilla, Human, Orangutan; Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: CEBPG / CEBP Gamma; Polyclonal Antibody; Goat Polyclonal to Human CEBPG / CEBP Gamma; Anti-CEBPG / CEBP Gamma Antibody (C-Terminus) IHC-plus; CEBPG; C/EBP gamma; GPE1BP; IG/EBP-1; Human CEBPG; CEBP Gamma; anti-CEBPG antibody

• Host: Goat
• Reactivity: Gorilla, Human, Orangutan; Predicted Reactivity: Gibbon, Monkey (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human CEBPG / CEBP Gamma.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 150

• Applicable Applications for anti-CEBPG antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:2000), IHC-P (2.5 - 3.75 ug/ml); Usage: Peptide ELISA: antibody detection limit dilution 1:2000. Western blot: Preliminary experiments gave an approx. 26kDa band in Human Lung lysates and in lysates of cell lines A549 after 1 ug/ml antibody staining. Please note that currently we cannot fi...
• Target Species: Human
• Immunogen Description: Synthetic peptide C-ENTTADGDNAGQ from the C-terminus of human CEBPG / CEBP Gamma (NP_001797.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan (100%); Gibbon, Monkey (92%); Panda (83%).
• Immunogen Type: Synthetic peptide
• Immunogen: CEBPG / CEBP Gamma antibody was raised against synthetic peptide C-ENTTADGDNAGQ from the C-terminus of human CEBPG / CEBP Gamma (NP_001797.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan (100%); Gibbon, Monkey (92%); Panda (83%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-CEBPG / CEBP Gamma antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Related Product Information for anti-CEBPG antibody

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other.

NCBI and Uniprot Product Information

• NCBI GI #: 4502769
• NCBI GeneID: 1054
• NCBI Accession #: NP_001797.1
• NCBI GenBank Nucleotide #: NM_001806.3
• UniProt Accession #: P53567; Q5U052; B2R946
• Molecular Weight: 16,408 Da
• NCBI Official Full Name: CCAAT/enhancer-binding protein gamma
• NCBI Official Synonym Full Names: CCAAT/enhancer binding protein (C/EBP), gamma
• NCBI Official Symbol: CEBPG
• NCBI Official Synonym Symbols: GPE1BP; IG/EBP-1
• NCBI Protein Information: CCAAT/enhancer-binding protein gamma; c/EBP gamma
• UniProt Protein Name: CCAAT/enhancer-binding protein gamma
• Protein Family: CCAAT/enhancer-binding protein
• UniProt Gene Name: CEBPG
• UniProt Synonym Gene Names: C/EBP gamma
• UniProt Entry Name: CEBPG_HUMAN

NCBI Description

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

C/EBP-gamma: Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Motility/polarity/chemotaxis; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; double-stranded DNA binding; transcription factor binding

Biological Process: positive regulation of DNA repair; transcription, DNA-dependent; natural killer cell mediated cytotoxicity; negative regulation of transcription factor activity; enucleate erythrocyte differentiation; liver development; mRNA metabolic process; regulation of transcription from RNA polymerase II promoter; B cell differentiation; positive regulation of transcription from RNA polymerase II promoter; immune response; positive regulation of transcription factor activity; positive regulation of DNA binding; positive regulation of interferon-gamma biosynthetic process