Rabbit B-Myb Polyclonal Antibody | anti-B-Myb antibody

B-Myb Rabbit Polyclonal

Cat. Num. AAA767158

• Gene Names: MYBL2; BMYB; B-MYB
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: B-Myb; Polyclonal Antibody; B-Myb Rabbit Polyclonal; anti-B-Myb antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 7

• Applicable Applications for anti-B-Myb antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
• Immunogen: V-myb myeloblastosis viral oncogene homolog (avian)-like 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Testing Data

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Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS767158 (B-Myb antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 559442
• NCBI GeneID: 4605
• Molecular Weight: 75,865 Da
• NCBI Official Full Name: B-Myb, partial
• NCBI Official Synonym Full Names: MYB proto-oncogene like 2
• NCBI Official Symbol: MYBL2
• NCBI Official Synonym Symbols: BMYB; B-MYB
• NCBI Protein Information: myb-related protein B
• UniProt Protein Name: Myb-related protein B
• UniProt Gene Name: MYBL2
• UniProt Synonym Gene Names: BMYB; B-Myb
• UniProt Entry Name: MYBB_HUMAN

NCBI Description

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Uniprot Description

B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 20q13.1

Cellular Component: nucleoplasm

Molecular Function: protein binding; transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; transcription from RNA polymerase II promoter