Western Blot (WB)
(Western blot analysis of ATM (pS1987) expression in HEK293T (A); Raw264.7 (B) whole cell lysates.)
Rabbit ATM Polyclonal Antibody | anti-ATM antibody
ATM Antibody
Gene Names
ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
ATM; Polyclonal Antibody; ATM Antibody; Purified Polyclonal ATM Antibody; Polyclonal ATM antibody; Anti-ATM antibody; ATM antibody; Serine-protein kinase ATM antibody; Ataxia telangiectasia mutated antibody; A-T mutated antibody; anti-ATM antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of ATM protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
3056
Applicable Applications for anti-ATM antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
ATM antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM (pS1987) as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of ATM (pS1987) expression in HEK293T (A); Raw264.7 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of ATM (pS1987) expression in HEK293T (A); Raw264.7 (B) whole cell lysates.)
Related Product Information for anti-ATM antibody
ATM and ATR (Ataxia telangiectasia and Rad3 related) are closely related kinases that are activated by DNA damage. These serine-threonine protein kinases are part of the phosphatidylinositol 3' kinase-like kinase (PIKK) family.
Product Categories/Family for anti-ATM antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
ATM
NCBI Official Synonym Full Names
ATM serine/threonine kinase
NCBI Official Symbol
ATM
NCBI Official Synonym Symbols
AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1
NCBI Protein Information
serine-protein kinase ATM
Protein Family
NCBI Description
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
Research Articles on ATM
Similar Products
Product Notes
The ATM (Catalog #AAA5315865) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ATM can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the ATM for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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