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SDS-Page

Cathepsin E Recombinant Protein | Ctse recombinant protein

Cathepsin E, 21-397aa, Mouse, His tag, Baculovirus

Gene Names
Ctse; CE; CatE; A430072O03Rik; C920004C08Rik
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Cathepsin E; 21-397aa; Mouse; His tag; Baculovirus; CTSE; A430072003Rik; C920004C08Rik; CatE; CE; Ctse recombinant protein
Ordering
For Research Use Only!
Host
Baculovirus
Purity/Purification
> 95% by SDS-PAGE
Form/Format
In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence
ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH
Sequence Length
397
Applicable Applications for Ctse recombinant protein
SDS-PAGE
Antigen Species
Mouse
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for Ctse recombinant protein
CTSE, also known as cathepsin E, belongs to an intracellular aspartic protease of the pepsin family. It plays an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. It is efficient in cleaving the Swedish mutant of amyloid precursor protein (APP) at the B site but show almost on reactivity with the wild-type APP. Recombinant mouse CTSE, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for Ctse recombinant protein
References
Tsukuba T., et al. (2000) Mol. Cells 10:601-611.; Bennett K., et al. (1992) Eur. J. Immunol. 22: 1519-1524.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41.8kDa (385aa) 40-57KDa (SDS-PAGE under reducing conditions.)
NCBI Official Full Name
cathepsin E preproprotein
NCBI Official Synonym Full Names
cathepsin E
NCBI Official Symbol
Ctse
NCBI Official Synonym Symbols
CE; CatE; A430072O03Rik; C920004C08Rik
NCBI Protein Information
cathepsin E
UniProt Protein Name
Cathepsin E
Protein Family
UniProt Gene Name
Ctse

NCBI Description

This gene encodes a member of the peptidase A1 family of aspartate proteases and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. Homozygous knockout mice for this gene exhibit lysosomal storage disorder, impaired autophagy, mitochondrial abnormalities, dermatitis, and reduced weight gain in an obesity model. [provided by RefSeq, Aug 2015]

Uniprot Description

May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

Research Articles on Ctse

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Product Notes

The Ctse ctse (Catalog #AAA206215) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's Cathepsin E can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the Ctse ctse for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ALHRVPLRRH QSLRKKLRAQ GQLSEFWRSH NLDMTRLSES CNVYSSVNEP LINYLDMEYF GTISIGTPPQ NFTVIFDTGS SNLWVPSVYC TSPACKAHPV FHPSQSDTYT EVGNHFSIQY GTGSLTGIIG ADQVSVEGLT VDGQQFGESV KEPGQTFVNA EFDGILGLGY PSLAAGGVTP VFDNMMAQNL VALPMFSVYL SSDPQGGSGS ELTFGGYDPS HFSGSLNWIP VTKQAYWQIA LDGIQVGDTV MFCSEGCQAI VDTGTSLITG PPDKIKQLQE AIGATPIDGE YAVDCATLDT MPNVTFLINE VSYTLNPTDY ILPDLVEGMQ FCGSGFQGLD IPPPAGPLWI LGDVFIRQFY SVFDRGNNQV GLAPAVPLEH HHHHH. It is sometimes possible for the material contained within the vial of "Cathepsin E, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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