Western Blot (WB)
(Western blot analysis of Raji Hela and A431 cell lysates using ATAD3A Polyclonal Antibody at dilution of 1:400)
Rabbit ATAD3A Polyclonal Antibody | anti-ATAD3A antibody
ATAD3A Polyclonal Antibody
IHC: 1:25-1:100
ELISA: 1:5000-1:10000
Western Blot (WB)
(Western blot analysis of Raji Hela and A431 cell lysates using ATAD3A Polyclonal Antibody at dilution of 1:400)
Western Blot (WB)
(Western blot analysis of Raji Hela and A431 cell lysates using ATAD3A Polyclonal Antibody at dilution of 1:400)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ATAD3A Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ATAD3A Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using ATAD3A Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using ATAD3A Polyclonal Antibody at dilution of 1:30(×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
Uniprot Description
ATAD3A: Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane
Molecular Function: ATP binding
Biological Process: cell growth; negative regulation of apoptosis
Research Articles on ATAD3A
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Product Notes
The ATAD3A atad3a (Catalog #AAA2562357) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATAD3A Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ATAD3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:25-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the ATAD3A atad3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATAD3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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