Mouse anti-Human ATAD3A Monoclonal Antibody | anti-ATAD3A antibody

ATAD3A Mouse mAb

Cat. Num. AAA435257

• Gene Names: ATAD3A; HAYOS
• Reactivity: Human
• Applications: Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay
• Synonyms: ATAD3A; Monoclonal Antibody; ATAD3A Mouse mAb; AAA-ATPase TOB3; ATPase family AAA domain-containing protein 3; ATPase family AAA domain-containing protein 3A; RP5-832C2.1; anti-ATAD3A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG
• Sequence Length: 586

• Applicable Applications for anti-ATAD3A antibody: Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Application Notes: WB: 1:1000-1:5000; IP: 10 tests; FC/FACS: 1:100-1:200
• Source Note: This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to ATD3A protein.
• Preparation and Storage: Store at -20 degree C. Stable for one year from the date of shipment.

Western Blot (WB)

Immunoprecipitation (IP)

Flow Cytometry (FC/FACS)

Related Product Information for anti-ATAD3A antibody

ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids.

Product Categories/Family for anti-ATAD3A antibody

Membrane; Lung Cancer

NCBI and Uniprot Product Information

• NCBI GI #: 283436222
• NCBI GeneID: 55210
• NCBI Accession #: NP_001164006.1
• NCBI GenBank Nucleotide #: NM_001170535.2
• UniProt Accession #: Q9NVI7; Q5SV23; Q8N275; Q96A50; B3KPB3; D2K8Q1; G3V1I6
• Molecular Weight: Predicted MW: 66kDa
• NCBI Official Full Name: ATPase family AAA domain-containing protein 3A isoform 2
• NCBI Official Synonym Full Names: ATPase family, AAA domain containing 3A
• NCBI Official Symbol: ATAD3A
• NCBI Official Synonym Symbols: HAYOS
• NCBI Protein Information: ATPase family AAA domain-containing protein 3A
• UniProt Protein Name: ATPase family AAA domain-containing protein 3A
• Protein Family: ATPase family AAA domain-containing protein
• UniProt Gene Name: ATAD3A

NCBI Description

This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

Uniprot Description

Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.