Rabbit anti-Human, Mouse ASB3 Polyclonal Antibody | anti-ASB3 antibody

ASB3, NT (ASB3, Ankyrin repeat and SOCS box protein 3) (FITC)

Cat. Num. AAA6275548

• Gene Names: ASB3; ASB-3
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ASB3; Polyclonal Antibody; NT (ASB3; Ankyrin repeat and SOCS box protein 3) (FITC); Ankyrin repeat and SOCS box protein 3; anti-ASB3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 445

• Applicable Applications for anti-ASB3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human ASB3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of ASB3 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in A549 cell line lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.)

Western Blot (WB)

(Western blot analysis of ASB3 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse spleen tissue lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.)

Related Product Information for anti-ASB3 antibody

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

Product Categories/Family for anti-ASB3 antibody

Antibodies; SOCS

References

Yang, Q., et al. BMC Med. Genet. 8 SUPPL 1, S12 (2007): Chung, A.S., et al. Mol. Cell. Biol. 25(11):4716-4726(2005). Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002). Kile, B.T., et al. Mol. Cell. Biol. 21(18):6189-6197(2001). Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000).

NCBI and Uniprot Product Information

• NCBI GI #: 22208951
• NCBI GeneID: 51130
• NCBI Accession #: NP_665862.1; NP_057199.1
• NCBI GenBank Nucleotide #: NP_665862.1
• UniProt Accession #: Q9Y575
• NCBI Official Full Name: ankyrin repeat and SOCS box protein 3 isoform b
• NCBI Official Synonym Full Names: ankyrin repeat and SOCS box containing 3
• NCBI Official Symbol: ASB3
• NCBI Official Synonym Symbols: ASB-3
• NCBI Protein Information: ankyrin repeat and SOCS box protein 3
• UniProt Protein Name: Ankyrin repeat and SOCS box protein 3
• Protein Family: Ankyrin repeat and SOCS box protein
• UniProt Gene Name: ASB3
• UniProt Synonym Gene Names: ASB-3
• UniProt Entry Name: ASB3_HUMAN

NCBI Description

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]