Rabbit Angio-associated migratory cell protein Polyclonal Antibody | anti-AAMP antibody
Anti-AAMP Antibody
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human
Testing Data
(Anti-AAMP Picoband antibody, MBS177473-1.jpgAll lanes: Anti AAMP (MBS177473) at 0.5ug/mlWB: Recombinant Human AAMP Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
Testing Data
(Anti-AAMP Picoband antibody, MBS177473-2.jpgAll lanes: Anti AAMP (MBS177473) at 0.5ug/mlLane 1: A431 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugLane 4: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 47KDObserved bind size: 47KD )
Immunohistochemistry (IHC)
(Anti-AAMP Picoband antibody, MBS177473-3.JPGIHC(P): Human Mammary Cancer Tissue )
Background: AAMP, also known as Angio-associated, migratory cell protein, is a protein which in humans is encoded by the AAMP gene. It is mapped to 2q35. The gene product of AAMP is an immunoglobulin-type protein, which is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. It has been demonstrated that an AAMP peptide containing the putative heparan sulfate-binding domain binds to heparin and mediates heparin-sensitive cell adhesion. AAMP plays a role in angiogenesis and cell migration. In smooth muscle cell migration, it may act through the RhoA pathway.
NCBI and Uniprot Product Information
NCBI Description
The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]
Uniprot Description
AAMP: Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.
Protein type: Cell surface; Motility/polarity/chemotaxis; Cell development/differentiation
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: cell surface; cytoplasm; plasma membrane
Molecular Function: heparin binding
Biological Process: smooth muscle cell migration; angiogenesis; cell differentiation
Research Articles on AAMP
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Product Notes
The AAMP aamp (Catalog #AAA177473) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-AAMP Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Angio-associated migratory cell protein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC-P). Western Blot: Concentration: 0.1-0.5mug/ml; Tested Species: Human Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human. Researchers should empirically determine the suitability of the AAMP aamp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angio-associated migratory cell protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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