Western Blot (WB)
Rabbit anti-Human ALS2CL Polyclonal Antibody | anti-ALS2CL antibody
Anti-ALS2CL Antibody
Gene Names
ALS2CL; RN49018
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
ALS2CL; Polyclonal Antibody; Anti-ALS2CL Antibody; anti-ALS2CL antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
953
Applicable Applications for anti-ALS2CL antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA titer: 1:5,000-1:10,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user.
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Raised against a peptide from C terminal residues of human ALS2CL protein.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-ALS2CL antibody
Rabbit polyclonal ALS2CL
References
(1) Lee,D.J., Schonleben,F., Banuchi,V.E. et al. Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis. Cancer Biol. Ther. 10 (7), 689-693 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,998 Da
NCBI Official Full Name
ALS2 C-terminal-like protein isoform 1
NCBI Official Synonym Full Names
ALS2 C-terminal like
NCBI Official Symbol
ALS2CL
NCBI Official Synonym Symbols
RN49018
NCBI Protein Information
ALS2 C-terminal-like protein
UniProt Protein Name
ALS2 C-terminal-like protein
Protein Family
UniProt Gene Name
ALS2CL
UniProt Entry Name
AL2CL_HUMAN
Uniprot Description
ALS2CL: Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: cytoplasmic membrane-bound vesicle
Molecular Function: identical protein binding; Rho guanyl-nucleotide exchange factor activity; GTPase activator activity; Rab GTPase binding
Biological Process: protein localization; endosome organization and biogenesis
Research Articles on ALS2CL
Similar Products
Product Notes
The ALS2CL als2cl (Catalog #AAA416327) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ALS2CL Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALS2CL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Peptide ELISA titer: 1:5,000-1:10,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the ALS2CL als2cl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALS2CL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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