Western Blot (WB)
(Western blot analysis of AKIR1 Antibody (C-term) in Hela cell line lysates (35ug/lane).AKIR1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human AKIR1 Polyclonal Antibody | anti-AKIRIN1 antibody
AKIR1 Antibody (C-term)
Gene Names
AKIRIN1; STRF2; C1orf108
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AKIR1; Polyclonal Antibody; AKIR1 Antibody (C-term); Akirin-1; AKIRIN1; C1orf108; anti-AKIRIN1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AKIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the C-terminal region of human AKIR1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
131-158
Sequence Length
147
Applicable Applications for anti-AKIRIN1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of AKIR1 Antibody (C-term) in Hela cell line lysates (35ug/lane).AKIR1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of AKIR1 Antibody (C-term) in Hela cell line lysates (35ug/lane).AKIR1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-AKIRIN1 antibody
The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the transcription of NF-kB dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways. AKIRIN1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.
References
Goto, A., et al. Nat. Immunol. 9(1):97-104(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21867
NCBI Official Full Name
akirin-1 isoform 2
NCBI Official Synonym Full Names
akirin 1
NCBI Official Symbol
AKIRIN1
NCBI Official Synonym Symbols
STRF2; C1orf108
NCBI Protein Information
akirin-1
UniProt Protein Name
Akirin-1
Protein Family
UniProt Gene Name
AKIRIN1
UniProt Synonym Gene Names
C1orf108
UniProt Entry Name
AKIR1_HUMAN
Uniprot Description
AKIRIN1: Belongs to the akirin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 1p34.3
Cellular Component: nucleoplasm; nuclear membrane; nucleus
Similar Products
Product Notes
The AKIRIN1 akirin1 (Catalog #AAA9202961) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 131-158. The AKIR1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AKIR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AKIRIN1 akirin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKIR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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