Rabbit Rab23 Polyclonal Antibody | anti-Rab23 antibody

Rab23 Rabbit Polyclonal

Cat. Num. AAA7603239

• Gene Names: RAB23; HSPC137
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: Rab23; Polyclonal Antibody; Rab23 Rabbit Polyclonal; anti-Rab23 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 237

• Applicable Applications for anti-Rab23 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: RAB23, member RAS oncogene family
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using MBS7603239 (RAB23 Antibody) at dilution of 1:200)

Western Blot (WB)

(mouse brain tissue were subjected to SDS PAGE followed by western blot with MBS7603239 (RAB23 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 6475048
• NCBI GeneID: 51715
• Molecular Weight: 26,659 Da
• NCBI Official Full Name: RAB23 protein
• NCBI Official Synonym Full Names: RAB23, member RAS oncogene family
• NCBI Official Symbol: RAB23
• NCBI Official Synonym Symbols: HSPC137
• NCBI Protein Information: ras-related protein Rab-23
• UniProt Protein Name: Ras-related protein Rab-23
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB23
• UniProt Entry Name: RAB23_HUMAN

NCBI Description

This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

RAB23: Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2). A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric, Rab; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 6p11

Cellular Component: autophagic vacuole; cytoplasm; endosome membrane; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane

Molecular Function: GTP binding; GTPase activity; protein binding

Biological Process: autophagic vacuole formation; cellular defense response; cilium biogenesis; intracellular protein transport; metabolic process; negative regulation of transcription factor import into nucleus; nucleocytoplasmic transport; small GTPase mediated signal transduction

Disease: Carpenter Syndrome 1