Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (AHNAK2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.)

Rabbit AHNAK2 Polyclonal Antibody | anti-AHNAK2 antibody

AHNAK2 Polyclonal Antibody

Gene Names
AHNAK2; C14orf78
Reactivity
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Applications
Immunohistochemistry
Purity
affinity purified by Protein A
Synonyms
AHNAK2; Polyclonal Antibody; AHNAK2 Polyclonal Antibody; AHNAK nucleoprotein 2; C14orf78; AHNAK 2; chromosome 14 open reading frame 78; KIAA2019; AHNK2_HUMAN.; anti-AHNAK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Clonality
Polyclonal
Specificity
AHNAK2 Polyclonal Antibody detects endogenous levels of AHNAK2 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-AHNAK2 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-500
Immunogen
KLH conjugated synthetic peptide derived from human AHNAK2:1201-1300/5795
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (AHNAK2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.)

Immunohistochemistry (IHC) (Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (AHNAK2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.)
Related Product Information for anti-AHNAK2 antibody
AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
605,648 Da
NCBI Official Full Name
protein AHNAK2 isoform 1
NCBI Official Synonym Full Names
AHNAK nucleoprotein 2
NCBI Official Symbol
AHNAK2
NCBI Official Synonym Symbols
C14orf78
NCBI Protein Information
protein AHNAK2
UniProt Protein Name
Protein AHNAK2
Protein Family
UniProt Gene Name
AHNAK2
UniProt Synonym Gene Names
C14orf78; KIAA2019

NCBI Description

This gene encodes a large nucleoprotein. The encoded protein has a tripartite domain structure with a relatively short N-terminus and a long C-terminus, separated by a large body of repeats. The N-terminal PSD-95/Discs-large/ZO-1 (PDZ)-like domain is thought to function in the formation of stable homodimers. The encoded protein may play a role in calcium signaling by associating with calcium channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

Uniprot Description

AHNAK2: a protein with a PDZ domain and 16 involucrin domains. Involucrin domains are glutamine-rich segments which are often cross-linked by tranglutaminase. A presumptive scaffold protein.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: costamere; cytoplasm; cytoplasmic vesicle membrane; cytosol; nucleus; plasma membrane; sarcolemma; T-tubule; Z disc

Molecular Function: protein binding

Biological Process: plasma membrane repair

Research Articles on AHNAK2

Similar Products

Product Notes

The AHNAK2 ahnak2 (Catalog #AAA3005607) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AHNAK2 Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's AHNAK2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-500. Researchers should empirically determine the suitability of the AHNAK2 ahnak2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AHNAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.