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Testing Data (Immunofluorescent staining of the TSA-treated and non-treated melanoma cells)

Rabbit Acetylated Lysine Polyclonal Antibody

Anti-Acetylated Lysine, FITC

Applications
Immunofluorescence
Synonyms
Acetylated Lysine; Polyclonal Antibody; Anti-Acetylated Lysine; FITC; Anti-Acetylated Lysine Antibody (Anti-Ack) FITC Conjugates; anti-Acetylated Lysine antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Affinity purified rabbit polyclonal anti-acetylated lysine antibodies. It was developed using a unique technique that utilizes the acetylated KLH as immunogen and the acetylated lysine-specific antibodies. It was specifically purified with immobilized acetylated lysine on agarose. The purified antibody is conjugated to fluorescein isothiocyanate
Form/Format
250ug/mL antibody stored in PBS, pH 7, with 50% glycerol
Applicable Applications for anti-Acetylated Lysine antibody
Immunofluorescence (IF)
Application Notes
For direct immunofluorescence experiments
Immunogen
Acetylated KLH conjugates
Preparation and Storage
Store product at -20 0C. Three years from date of shipping

Testing Data

(Immunofluorescent staining of the TSA-treated and non-treated melanoma cells)

Testing Data (Immunofluorescent staining of the TSA-treated and non-treated melanoma cells)
Related Product Information for anti-Acetylated Lysine antibody
Acetylation of lysine is an important reversible modification. The activities of some proteins are controlled by acetylation of lysine. Histone acetyltransferases (HATs) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) that contain lysines residues. Histone deacetylases (HDACs) removes the acetyl group from the same residue. [1] Acetylation/deacetylation of histones results in cell signaling processes that include gene activity, cell growth, differentiation and apoptosis. [2] In cancer and polyglutamine diseases, the regulation of protein acetylation/deacetylation is impaired (7). Numerous anti-cancer drugs target HDACs. [3]

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Product Notes

The Acetylated Lysine (Catalog #AAA330101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Acetylated Lysine can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). For direct immunofluorescence experiments. Researchers should empirically determine the suitability of the Acetylated Lysine for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Acetylated Lysine, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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