Rabbit ABCA7 Polyclonal Antibody | anti-ABCA7 antibody
ABCA7 Polyclonal Antibody Cy3 Conjugated
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Purified by Protein A
Synonyms
ABCA7; Polyclonal Antibody; ABCA7 Polyclonal Antibody Cy3 Conjugated; ABC transporter ABCA7; ABC transporter member 7; ABCA SSN; ABCX; ATP binding cassette sub family A ABC1 member 7; ATP binding cassette sub family A member 7; ATP binding Cassette Transporter A7;; FLJ40025; Macrophage ABC transporter; ABCA7_HUMAN; anti-ABCA7 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-ABCA7 antibody
Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes
FC/FACS:1:20-10
IF: 1:50-200
IF: 1:50-200
Conjugation
Cy3
Excitation Emission
512,550nm 570,615nm
Immunogen
KLH conjugated synthetic peptide derived from human ABCA7
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-ABCA7 antibody
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Product Categories/Family for anti-ABCA7 antibody
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Product Notes
The ABCA7 (Catalog #AAA9460330) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCA7 Polyclonal Antibody Cy3 Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ABCA7 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Flow Cytometry (FC/FACS). FC/FACS:1:20-10 IF: 1:50-200. Researchers should empirically determine the suitability of the ABCA7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCA7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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