Testing Data
PIP4K2C recombinant protein
PIP4K2C, Active
Gene Names
PIP4K2C; PIP5K2C
Applications
Kinase Assay
Synonyms
PIP4K2C; Active; PIP4K2C recombinant protein
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Positions
Full length
Sequence Length
2937
Applicable Applications for PIP4K2C recombinant protein
Kinase Assay
Species
Human
Tag
GST tag
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Testing Data
Testing Data
Testing Data #2
Testing Data #2
Related Product Information for PIP4K2C recombinant protein
Description: Recombinant full-length human PIP4K2C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: PIP4K2C (also known as phosphatidylinositol-5-phosphate 4-kinase, type II, gamma) is a member of the PIP kinase family that plays an important role in a wide variety of cell functions (1). PIP4K2C is found in the cytosol and surrounding plasma membrane and its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis. PIP4K2C play an important role in the production of phosphatidylinositol bisphosphate (PIP2) in the endoplasmic reticulum (2).
Scientific Background: PIP4K2C (also known as phosphatidylinositol-5-phosphate 4-kinase, type II, gamma) is a member of the PIP kinase family that plays an important role in a wide variety of cell functions (1). PIP4K2C is found in the cytosol and surrounding plasma membrane and its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis. PIP4K2C play an important role in the production of phosphatidylinositol bisphosphate (PIP2) in the endoplasmic reticulum (2).
Product Categories/Family for PIP4K2C recombinant protein
References
1. Heck JN. et.al: A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family. Crit. Rev. Biochem. Mol. Biol. 2007 42:15-3. 2. Kanaho Y. et.al: The phosphoinositide kinase PIP5K that produces the versatile signaling phospholipid PI4,5P (2) Biol. Pharm. Bull. 2007 30:1605-9.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
75 kDa
NCBI Official Full Name
Homo sapiens phosphatidylinositol-5-phosphate 4-kinase, type II, gamma, mRNA
NCBI Official Synonym Full Names
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
NCBI Official Symbol
PIP4K2C
NCBI Official Synonym Symbols
PIP5K2C
NCBI Protein Information
phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
UniProt Protein Name
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Protein Family
UniProt Gene Name
PIP4K2C
UniProt Synonym Gene Names
PIP5K2C; PI(5)P 4-kinase type II gamma; PIP4KII-gamma
Uniprot Description
PIP4K2C: May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.149; Endoplasmic reticulum; Kinase, lipid; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: autophagic vacuole; cytosol
Molecular Function: 1-phosphatidylinositol-5-phosphate 4-kinase activity; identical protein binding
Biological Process: phosphatidylinositol biosynthetic process; regulation of autophagy; regulation of phosphoinositide 3-kinase cascade
Research Articles on PIP4K2C
Similar Products
Product Notes
The PIP4K2C pip4k2c (Catalog #AAA515621) is a Recombinant Protein produced from Sf9 insect cells using baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full length. AAA Biotech's PIP4K2C can be used in a range of immunoassay formats including, but not limited to, Kinase Assay. Researchers should empirically determine the suitability of the PIP4K2C pip4k2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIP4K2C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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