Human Progesterone induced blocking factor ELISA Kit | PIBF elisa kit
Human Progesterone induced blocking factor (PIBF) ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]
Uniprot Description
PIBF1: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 13q21.33-q22.1
Cellular Component: centrosome; cytosol; extracellular space; microtubule organizing center; nucleoplasm; nucleus
Molecular Function: interleukin-4 receptor binding; protein binding
Biological Process: activation of JAK protein; immune system process; mitotic metaphase plate congression; negative regulation of interleukin-12 production; negative regulation of natural killer cell activation; negative regulation of prostaglandin biosynthetic process; negative regulation of tyrosine phosphorylation of STAT protein; positive regulation of interleukin-10 production; positive regulation of tyrosine phosphorylation of STAT protein
Disease: Joubert Syndrome 33
Research Articles on PIBF
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Product Notes
The Human PIBF pibf1 (Catalog #AAA281811) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA281811 ELISA Kit recognizes Human PIBF. It is sometimes possible for the material contained within the vial of "Progesterone induced blocking factor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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