Tumor protein D53 (TPD52L1) Recombinant Protein | TPD52L1 recombinant protein
Recombinant Human Tumor protein D53 (TPD52L1)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
TPD52L1: a member of the tumor protein D52 (TPD52) family. Contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. Interacts with the apoptosis signal-regulating kinase 1 (ASK1) and positively regulates ASK1-induced apoptosis. Multiple alternatively spliced transcript variants have been observed.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 6q22-q23
Cellular Component: perinuclear region of cytoplasm; cytoplasm
Molecular Function: identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity
Biological Process: positive regulation of MAP kinase activity; positive regulation of JNK cascade; regulation of caspase activity; G2/M transition of mitotic cell cycle
Research Articles on TPD52L1
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Product Notes
The TPD52L1 tpd52l1 (Catalog #AAA1414077) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-144aa; Full Length. The amino acid sequence is listed below: MEAQAQGLLE TEPLQGTDED AVASADFSSM LSEEEKEELK AELVQLEDEI TTLRQVLSAK ERHLVEIKQK LGMNLMNELK QNFSKSWHDM QTTTAYKKTH ETLSHAGQKA TAAFSNVGTA ISKKFGDMSY SIRHSISMPA MRNSPTFKSF EERVETTVTS LKTKVGGTNP NGGSFEEVLS STAHASAQSL AGGSRRTKEE ELQC. It is sometimes possible for the material contained within the vial of "Tumor protein D53 (TPD52L1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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