Human Progesterone Immunomodulatory Binding Factor 1 (PIBF1) RTU ELISA Kit | PIBF1 rtu elisa kit

Human Progesterone Immunomodulatory Binding Factor 1 (PIBF1) ELISA Kit

Cat. Num. AAA4501821

• Gene Names: PIBF1; PIBF; CEP90; JBTS33; C13orf24
• Reactivity: Human
• Synonyms: Progesterone Immunomodulatory Binding Factor 1 (PIBF1); Human Progesterone Immunomodulatory Binding Factor 1 (PIBF1) ELISA Kit; PIBF; C13orf24; CEP90; Progesterone-Induced Blocking Factor 1; PIBF1 rtu elisa kit

• Reactivity: Human
• Sequence Length: 757

• Assay Type: Sandwich
• Samples: Tissue Homogenates or Other Biological Fluids.
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.116ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for PIBF1 rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to PIBF1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to PIBF1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain PIBF1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of PIBF1 in the samples is then determined by comparing the O.D. of the samples to the standard curve

NCBI and Uniprot Product Information

• NCBI GI #: 55769583
• NCBI GeneID: 10464
• NCBI Accession #: NP_006337.2
• NCBI GenBank Nucleotide #: NM_006346.3
• UniProt Accession #: Q8WXW3; O95664; Q6U9V2; Q6UG50; Q86V07; Q96SF4
• Molecular Weight: 35,071 Da
• NCBI Official Full Name: progesterone-induced-blocking factor 1 isoform 2
• NCBI Official Synonym Full Names: progesterone immunomodulatory binding factor 1
• NCBI Official Symbol: PIBF1
• NCBI Official Synonym Symbols: PIBF; CEP90; JBTS33; C13orf24
• NCBI Protein Information: progesterone-induced-blocking factor 1
• UniProt Protein Name: Progesterone-induced-blocking factor 1
• Protein Family: Progesterone-induced-blocking factor
• UniProt Gene Name: PIBF1
• UniProt Synonym Gene Names: C13orf24; PIBF; PIBF; CEP90

NCBI Description

This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]

Uniprot Description

Isoform 1: Pericentriolar protein required to maintain mitotic spindle pole integrity (PubMed:21224392). Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation (PubMed:23110211). Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2 (PubMed:26297806).