Programmed cell death protein 10 (Pdcd10) Recombinant Protein | Pdcd10 recombinant protein
Recombinant Rat Programmed cell death protein 10 (Pdcd10)
threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine
threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
NCBI and Uniprot Product Information
Uniprot Description
Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.
Research Articles on Pdcd10
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Product Notes
The Pdcd10 pdcd10 (Catalog #AAA1471547) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-210, full length protein. The amino acid sequence is listed below: MTMEEMKTEA EAASMVSMPL YAVMYPVFNE LERVNLSAAQ TLRAAFIKAE KENPGLTQDI IMKILEKKSV EVNFTESLLR MAADDVEEYM IERPEPEFQD LNEKARALKQ ILSKIPDEIN DRVRFLQTIK DIASAIKELL DTVNNVFKKY QYQNRRALEH QKKEFVKYSK SFSDTLKTYF KDGKAINVFI SANRLIHQTN LILQTFKTVA. It is sometimes possible for the material contained within the vial of "Programmed cell death protein 10 (Pdcd10), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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