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Parkinson Disease Protein 7 (PARK7) Recombinant Protein | PARK7 recombinant protein
Recombinant Parkinson Disease Protein 7 (PARK7)
MGHHHHHHSGSEF-MASKRALVIL AKGAEEMETV IPVDVMRRAG IKVTVAGLAG KDPVQCSRDV MICPDTSLED AKTQGPYDVV VLPGGNLGAQ NLSESPMVKE ILKEQESRKG LIAAICAGPT ALLAHEVGFG CKVTTHPLAK DKMMNGSHYS YSESRVEKDG LILTSRGPGT SFEFALAIVE ALVGKDMANQ VKAPLVLKD
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
Uniprot Description
DJ-1: associated with autosomal recessive early onset parkinsonism. Involved in the oxidative stress response. Three cysteines in DJ-1 may be oxidized to cysteine sulphonic acid in the cellular response to H2O2. Loss of DJ-1 function may lead to neurodegeneration.
Protein type: EC 3.4.-.-; Nuclear receptor co-regulator; Tumor suppressor; Transcription regulation
Cellular Component: neuron projection; membrane; mitochondrion; mitochondrial matrix; endoplasmic reticulum; cytoplasm; plasma membrane; mitochondrial intermembrane space; cytosol; nucleus
Molecular Function: peptidase activity; protein binding; peroxiredoxin activity; hydrolase activity; RNA binding; glyoxalase III activity; cysteine-type peptidase activity
Biological Process: synaptic transmission, dopaminergic; adult locomotory behavior; membrane hyperpolarization; proteolysis; glycolate biosynthetic process; single fertilization; enzyme active site formation via L-cysteine sulfinic acid; dopamine uptake; inflammatory response; mitochondrion organization and biogenesis; protein stabilization; detoxification of copper ion; methylglyoxal catabolic process to D-lactate; membrane depolarization; cell proliferation; response to hydrogen peroxide; detoxification of mercury ion; regulation of inflammatory response; negative regulation of ubiquitin-protein ligase activity; hydrogen peroxide metabolic process; autophagy; positive regulation of transcription from RNA polymerase II promoter; negative regulation of protein ubiquitination; negative regulation of protein catabolic process; negative regulation of apoptosis
Research Articles on PARK7
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Product Notes
The PARK7 park7 (Catalog #AAA2012481) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Parkinson Disease Protein 7 (PARK7) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the PARK7 park7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with a N-terminal His-tag, its sequence is listed below. MGHHHHHHSG SEF-MASKRA LVIL AKGAEEMETV IPVDVMRRAG IKVTVAGLAG KDPVQCSRDV MICPDTSLED AKTQGPYDVV VLPGGNLGAQ NLSESPMVKE ILKEQESRKG LIAAICAGPT ALLAHEVGFG CKVTTHPLAK DKMMNGSHYS YSESRVEKDG LILTSRGPGT SFEFALAIVE ALVGKDMANQ VKAPLVLKD. It is sometimes possible for the material contained within the vial of "Parkinson Disease Protein 7 (PARK7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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