SDS-PAGE
OBCAM / OPCML recombinant protein
Recombinant Mouse OBCAM / OPCML Protein (His tag)
Gene Names
Opcml; Gm181; Obcam; AI844366; 3732419F12; C230027C17; 2900075O15Rik; B930023M13Rik
Purity
> 95 % as determined by SDS-PAGE
Synonyms
OBCAM / OPCML; Recombinant Mouse OBCAM / OPCML Protein (His tag); OPCML; OBCAM / OPCML recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
337
Application Notes
The recombinant mouse OPCML comprises 295 amino acids and has a predicted molecular mass of 32.7 kDa. The apparent molecular mass of the protein is approximately 44-55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Thr 30
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for OBCAM / OPCML recombinant protein
Background: Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein, consists of three immunoglobulin (Ig)-like domains anchored to the membrane through a glycosylphosphatidylinositol (GPI)-tail. OPCML also belongs to the member of the IgLON family, a subgroup of the immunoglobulin superfamily, consisting of three members, LAMP, OBCAM, and Neurotrimin. These molecules interact homophilically and heterophilically within the family, and OBCAM acts only as heterodimers with LAMP or Neurotrimin and possibly inhibits neurite outgrowth from cerebellar granule cells. OBCAM has been presumed to play a role as a cell adhesion/recognition molecule. Furthermore, the OPCML protein defects may play an important role in the carcinogenesis of cervical or ovarian cancers, and this gene is regarded as a candidate TSG (tumor suppressor gene).
Description: A DNA sequence encoding the mouse OPCML (NP_808574.2) (Ala5-Val313) was expressed with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the mouse OPCML (NP_808574.2) (Ala5-Val313) was expressed with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
opioid-binding protein/cell adhesion molecule
NCBI Official Synonym Full Names
opioid binding protein/cell adhesion molecule-like
NCBI Official Symbol
Opcml
NCBI Official Synonym Symbols
Gm181; Obcam; AI844366; 3732419F12; C230027C17; 2900075O15Rik; B930023M13Rik
NCBI Protein Information
opioid-binding protein/cell adhesion molecule
Research Articles on OBCAM / OPCML
Similar Products
Product Notes
The OBCAM / OPCML (Catalog #AAA2546676) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse OPCML comprises 295 amino acids and has a predicted molecular mass of 32.7 kDa. The apparent molecular mass of the protein is approximately 44-55 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the OBCAM / OPCML for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OBCAM / OPCML, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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