Mouse nucleolar complex associated 2 homolog (S. cerevisiae) ELISA Kit | NOC2L elisa kit
Mouse Nucleolar complex protein 2 homolog, NOC2L ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NOC2L: Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. Belongs to the NOC2 family.
Protein type: Transcription factor; Histone-binding; Nucleolus; RNA-binding
Cellular Component: nucleoplasm; nucleolus; nucleus
Molecular Function: nucleosomal histone binding; histone binding; p53 binding; nucleosome binding; chromatin binding; transcription corepressor activity
Biological Process: nucleolus to nucleoplasm transport; regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; chromatin assembly; negative regulation of transcription from RNA polymerase II promoter; negative regulation of B cell apoptosis; negative regulation of histone acetylation
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Product Notes
The Mouse NOC2L noc2l (Catalog #AAA9342456) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342456 ELISA Kit recognizes Mouse NOC2L. It is sometimes possible for the material contained within the vial of "nucleolar complex associated 2 homolog (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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