Neurofibromin (NF1) Recombinant Protein | NF1 recombinant protein
Recombinant Human Neurofibromin (NF1) , partial
Gene Names
NF1; WSS; NFNS; VRNF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Neurofibromin (NF1); Recombinant Human Neurofibromin (NF1); partial; NF1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1566-1837. Partial
Sequence
SSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPD
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for NF1 recombinant protein
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
318,992 Da
NCBI Official Full Name
neurofibromin isoform 2
NCBI Official Synonym Full Names
neurofibromin 1
NCBI Official Symbol
NF1
NCBI Official Synonym Symbols
WSS; NFNS; VRNF
NCBI Protein Information
neurofibromin
UniProt Protein Name
Neurofibromin
Protein Family
UniProt Gene Name
NF1
NCBI Description
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
Research Articles on NF1
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Product Notes
The NF1 nf1 (Catalog #AAA953948) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1566-1837. Partial. The amino acid sequence is listed below: SSKFEEFMTR HQVHEKEEFK ALKTLSIFYQ AGTSKAGNPI FYYVARRFKT GQINGDLLIY HVLLTLKPYY AKPYEIVVDL THTGPSNRFK TDFLSKWFVV FPGFAYDNVS AVYIYNCNSW VREYTKYHER LLTGLKGSKR LVFIDCPGKL AEHIEHEQQK LPAATLALEE DLKVFHNALK LAHKDTKVSI KVGSTAVQVT SAERTKVLGQ SVFLNDIYYA SEIEEICLVD ENQFTLTIAN QGTPLTFMHQ ECEAIVQSII HIRTRWELSQ PD . It is sometimes possible for the material contained within the vial of "Neurofibromin (NF1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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