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Never In Mitosis Gene A Related Kinase 2 (NEK2) Recombinant Protein | NEK2 recombinant protein
Recombinant Never In Mitosis Gene A Related Kinase 2 (NEK2)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-FLD SKHNVKLGDF GLARILNHDT SFAKTFVGTP YYMSPEQMSC LSYNEKSDIW SLGCLLYELC ALMPPFTAFN QKELAGKIRE GRFRRIPYRY SDGLNDLITR MLNLKDYHRP SVEEILESPL IADLVAEEQR RNLERRGRRS GEPSKLPDSS PVLSELKLKE RQLQDREQAL RAREDILEQK ERELCIRERL AEDKLARAES LMKNYSLLKE HRLLCLAGGP ELDLPSSAMK KKVHFHGESK ENTARSE
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
Uniprot Description
NEK2: a protein kinase of the NEK family. Accumulates throughout S phase and shows maximal levels in late G2. This expression pattern is highly reminiscent of that of A and B cyclins. Phosphorylation of Hec1 by Nek2 is essential for faithful chromosome segregation
Protein type: Nucleolus; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, Other; EC 2.7.11.1; Other group; NEK family
Cellular Component: spindle pole; centrosome; microtubule; protein complex; condensed nuclear chromosome; chromosome; kinetochore; intercellular bridge; cytoskeleton; cytoplasm; midbody; nucleus; chromosome, pericentric region
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein phosphatase binding; ATP binding; protein kinase activity
Biological Process: mitosis; regulation of attachment of spindle microtubules to kinetochore; blastocyst development; meiotic cell cycle; mitotic sister chromatid segregation; cell division; protein amino acid autophosphorylation; centrosome separation; cell cycle; protein amino acid phosphorylation; phosphorylation; negative regulation of DNA binding; chromosome segregation
Research Articles on NEK2
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Product Notes
The NEK2 nek2 (Catalog #AAA2011890) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Never In Mitosis Gene A Related Kinase 2 (NEK2) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the NEK2 nek2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-FLD SKHNVKLGDF GLARILNHDT SFAKTFVGTP YYMSPEQMSC LSYNEKSDIW SLGCLLYELC ALMPPFTAFN QKELAGKIRE GRFRRIPYRY SDGLNDLITR MLNLKDYHRP SVEEILESPL IADLVAEEQR RNLERRGRRS GEPSKLPDSS PVLSELKLKE RQLQDREQAL RAREDILEQK ERELCIRERL AEDKLARAES LMKNYSLLKE HRLLCLAGGP ELDLPSSAMK KKVHFHGESK ENTARSE. It is sometimes possible for the material contained within the vial of "Never In Mitosis Gene A Related Kinase 2 (NEK2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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