Pre-B-Lymphocyte Gene 1 (VPREB1) Recombinant Protein | VPREB1 recombinant protein

Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1)

Cat. Num. AAA2018412

• Gene Names: Vpreb1; CD179a; Vpreb-1
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Pre-B-Lymphocyte Gene 1 (VPREB1); Recombinant Pre-B-Lymphocyte Gene 1 (VPREB1); VPREB1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- PPLAS SSLGATIRLS CTLSNDHNIG IYSIYWYQQR PGHPPRFLLR YFSHSDKHQG PDIPPRFSGS KDTTRNLGYLSISELQPEDE AVYYCAVGLR SQEKKRMERE WEGE
• Sequence Length: 142

• Applicable Applications for VPREB1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Pro26~Glu134 (Accession # P13372) with two N-terminal Tags, His-tag and T7-tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 7.9
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 8850238
• NCBI GeneID: 22362
• NCBI Accession #: NP_058678.1
• NCBI GenBank Nucleotide #: NM_016982.2
• UniProt Accession #: P13372
• Molecular Weight: 16.4kDa
• NCBI Official Full Name: immunoglobulin iota chain
• NCBI Official Synonym Full Names: pre-B lymphocyte gene 1
• NCBI Official Symbol: Vpreb1
• NCBI Official Synonym Symbols: CD179a; Vpreb-1
• NCBI Protein Information: immunoglobulin iota chain
• UniProt Protein Name: Immunoglobulin iota chain
• Protein Family: Immunoglobulin
• UniProt Gene Name: Vpreb1
• UniProt Entry Name: VPRE1_MOUSE

Uniprot Description

VPREB1: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation. Belongs to the immunoglobulin superfamily.

Cellular Component: plasma membrane; external side of plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: B cell proliferation; cell morphogenesis; homeostasis of number of cells; hemopoiesis; immune response; immunoglobulin production; regulation of cell size