Cytoplasmic protein NCK1 (Nck1) Recombinant Protein | Nck1 recombinant protein
Recombinant Mouse Cytoplasmic protein NCK1 (Nck1)
NCBI and Uniprot Product Information
Uniprot Description
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA ().
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Product Notes
The Nck1 nck1 (Catalog #AAA1338624) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-377, full length protein. The amino acid sequence is listed below: AEEVVVVAKF DYVAQQEQEL DIKKNERLWL LDDSKSWWRV RNSMNKTGFV PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDTAS PADDSFVDPG ERLYDLNMPA FVKFNYMAER EDELSLIKGT KVIVMEKCSD GWWRGSYNGQ IGWFPSNYVT EEGDSPLGDH VGSLSEKLAA VVNNLNTGQV LHVVQALYPF SSSNDEELNF EKGDVMDVIE KPENDPEWWK CRKINGMVGL VPKNYVTIMQ NNPLTSGLEP SPPQCDYIRP SLTGKFAGNP WYYGKVTRHQ AEMALNERGH EGDFLIRDSE SSPNDFSVSL KAQGKNKHFK VQLKETVYCI GQRKFSTMEE LVEHYKKAPI FTSEQGEKLY LVKHLS. It is sometimes possible for the material contained within the vial of "Cytoplasmic protein NCK1 (Nck1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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