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SDS-PAGE (SDS-PAGE analysis of recombinant MTCH2 on Coomassie Blue-stained 12% SDS-PAGE gel.)

Mtch2 recombinant protein

MTCH2 Recombinant Protein

Gene Names
Mtch2; HSPC032; 2310034D24Rik; 4930539J07Rik
Applications
ELISA, Western Blot
Purity
~95%
Synonyms
MTCH2; MTCH2 Recombinant Protein; MTCH2 Recombinant Protein: HSPC032; 2310034D24Rik; 4930539J07Rik; Mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2 recombinant protein
Ordering
For Research Use Only!
Purity/Purification
~95%
Form/Format
Liquid
Sequence
aa 29 - 174
Sequence Length
303
Applicable Applications for Mtch2 recombinant protein
ELISA (EIA), Western Blot (WB), MS
Application Notes
This recombinant protein can be used for WB, ELISA, MS and neutralization assays. For research use only.
Species
Mouse
Source
E Coli
Buffer
1X PBS containing 0.1% SDS
Fusion Tag
Fusion Partner: C-terminal His-tag
Preparation and Storage
Store in working aliquots at -70 degree C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

SDS-PAGE

(SDS-PAGE analysis of recombinant MTCH2 on Coomassie Blue-stained 12% SDS-PAGE gel.)

SDS-PAGE (SDS-PAGE analysis of recombinant MTCH2 on Coomassie Blue-stained 12% SDS-PAGE gel.)
Related Product Information for Mtch2 recombinant protein
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals (4-6), suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19 kDa (Calculated)
NCBI Official Full Name
mitochondrial carrier homolog 2
NCBI Official Synonym Full Names
mitochondrial carrier homolog 2 (C. elegans)
NCBI Official Symbol
Mtch2
NCBI Official Synonym Symbols
HSPC032; 2310034D24Rik; 4930539J07Rik
NCBI Protein Information
mitochondrial carrier homolog 2
UniProt Protein Name
Mitochondrial carrier homolog 2
Protein Family
UniProt Gene Name
Mtch2
UniProt Entry Name
MTCH2_MOUSE

Uniprot Description

MTCH2: The substrate transported is not yet known. Induces mitochondrial depolarization. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Mitochondrial

Cellular Component: mitochondrial outer membrane; membrane; mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus

Biological Process: transport

Research Articles on Mtch2

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Product Notes

The Mtch2 mtch2 (Catalog #AAA153299) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MTCH2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), MS. This recombinant protein can be used for WB, ELISA, MS and neutralization assays. For research use only. Researchers should empirically determine the suitability of the Mtch2 mtch2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: aa 29 - 174. It is sometimes possible for the material contained within the vial of "MTCH2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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