Immunocytochemistry (ICC)
(Immunocytochemistry analysis of NTAL by confocal microscopy in THP-1 human acute monocytic leukemia cell line. The cells were permeabilized and immunostained using anti-NTAL (NAP-07; green). Nuclei are vizualized by propidium iodide (red).)
Mouse anti-Human, Mouse NTAL Antibody | anti-NTAL antibody
Anti-NTAL Purified
Gene Names
Lat2; LAB; NTAL; WSCR5; Wbscr5; Wbscr15; AW125574
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation, Western Blot, Immunocytochemistry
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
NTAL; Anti-NTAL Purified; linker for activation of T cells family member 2; LAB; LAT2; anti-NTAL antibody
Host
Mouse
Reactivity
Human, Mouse
Isotype
IgG1
Clone Number
NAP-07
Specificity
The antibody NAP-07 reacts with an intracellular epitope of Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B lymphocytes, NK cells and myeloid cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
203
Applicable Applications for anti-NTAL antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Recombinant cytoplasmic domain (aa 91-243) of human NTAL.
Preparation and Storage
Store at 2-8 degree C.
Immunocytochemistry (ICC)
(Immunocytochemistry analysis of NTAL by confocal microscopy in THP-1 human acute monocytic leukemia cell line. The cells were permeabilized and immunostained using anti-NTAL (NAP-07; green). Nuclei are vizualized by propidium iodide (red).)
Immunocytochemistry (ICC)
(Immunocytochemistry analysis of NTAL by confocal microscopy in THP-1 human acute monocytic leukemia cell line. The cells were permeabilized and immunostained using anti-NTAL (NAP-07; green). Nuclei are vizualized by propidium iodide (red).)
Related Product Information for anti-NTAL antibody
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
linker for activation of T-cells family member 2 isoform a
NCBI Official Synonym Full Names
linker for activation of T cells family, member 2
NCBI Official Symbol
Lat2
NCBI Official Synonym Symbols
LAB; NTAL; WSCR5; Wbscr5; Wbscr15; AW125574
NCBI Protein Information
linker for activation of T-cells family member 2
UniProt Protein Name
Linker for activation of T-cells family member 2
UniProt Gene Name
Lat2
UniProt Synonym Gene Names
Lab; Ntal; Wbscr15; Wbscr5
UniProt Entry Name
NTAL_MOUSE
Research Articles on NTAL
Similar Products
Product Notes
The NTAL lat2 (Catalog #AAA1801395) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-NTAL Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NTAL can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the NTAL lat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NTAL, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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