Testing Data
Rabbit anti-Rat NATL/LAB Polyclonal Antibody | anti-NATL/LAB antibody
NATL / LAB Antibody
Gene Names
Lat2; Ntal; Wbscr5
Reactivity
Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
NATL/LAB; Polyclonal Antibody; NATL / LAB Antibody; HSPC046; LAB; LAT2; NTAL; WBSCR15; WBSCR5; WSCR5; anti-NATL/LAB antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
204
Applicable Applications for anti-NATL/LAB antibody
Western Blot (WB)
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects a 22 kDa rat NTAL/LAB. Other species have not been determined.
Immunogen
Synthetic peptide surrounding amino acid 187 of rat NTAL
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-NATL/LAB antibody
Background: Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein. NTAL is expressed in B cells, mast cells, monocytes and NK cells. When NTAL is tyrosine phosphorylated, it recruits signalling molecules such as Grb2, Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,130 Da
NCBI Official Full Name
linker for activation of T-cells family member 2
NCBI Official Synonym Full Names
linker for activation of T cells family, member 2
NCBI Official Symbol
Lat2
NCBI Official Synonym Symbols
Ntal; Wbscr5
NCBI Protein Information
linker for activation of T-cells family member 2
UniProt Protein Name
Linker for activation of T-cells family member 2
UniProt Gene Name
Lat2
UniProt Synonym Gene Names
Lab; Ntal; Wbscr5
UniProt Entry Name
NTAL_RAT
NCBI Description
human homolog maps to the microdeletion region in Williams syndrome and may act as an adaptor for non T-cell immune response [RGD, Feb 2006]
Uniprot Description
LAB: linker for activation of B cells (LAB) is an adaptor protein. B cell antigen receptor signaling leads to its phosphorylation and interaction with the adaptor protein Grb2. Decreased expression leads to a reduction in BCR-mediated calcium flux and Erk activation. Localized to lipid rafts.
Protein type: Adaptor/scaffold; Membrane protein, integral
Cellular Component: mast cell granule; plasma membrane; integral to membrane; lipid raft
Molecular Function: SH2 domain binding
Biological Process: B cell receptor signaling pathway; B cell activation; calcium-mediated signaling; mast cell degranulation
Research Articles on NATL/LAB
Similar Products
Product Notes
The NATL/LAB lat2 (Catalog #AAA841201) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NATL / LAB Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NATL/LAB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects a 22 kDa rat NTAL/LAB. Other species have not been determined. Researchers should empirically determine the suitability of the NATL/LAB lat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NATL/LAB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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