Mouse Wingless Type MMTV Integration Site Family, Member 10B (WNT10B) ELISA Kit | WNT10B elisa kit

Mouse Wingless Type MMTV Integration Site Family, Member 10B (WNT10B) ELISA Kit

Cat. Num. AAA450002

• Gene Names: Wnt10b; Wnt12
• Reactivity: Mouse
• Synonyms: Wingless Type MMTV Integration Site Family; Member 10B (WNT10B); Mouse Wingless Type MMTV Integration Site Family; Member 10B (WNT10B) ELISA Kit; WNT-12; SHFM6; WNT10B elisa kit

• Reactivity: Mouse
• Sequence Length: 389

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.056ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 6756003
• NCBI GeneID: 22410
• NCBI Accession #: NP_035848.1
• NCBI GenBank Nucleotide #: NM_011718.2
• UniProt Accession #: P48614; P70702
• Molecular Weight: 32,400 Da
• NCBI Official Full Name: protein Wnt-10b
• NCBI Official Synonym Full Names: wingless-type MMTV integration site family, member 10B
• NCBI Official Symbol: Wnt10b
• NCBI Official Synonym Symbols: Wnt12
• NCBI Protein Information: protein Wnt-10b
• UniProt Protein Name: Protein Wnt-10b
• UniProt Gene Name: Wnt10b
• UniProt Synonym Gene Names: Wnt-10b; Wnt10; Wnt12

Uniprot Description

WNT10B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Defects in WNT10B are the cause of split-hand/foot malformation type 6 (SHFM6). SHFM is a limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. SHFM6 is a autosomal recessive disorder. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: frizzled binding; receptor binding

Biological Process: cell cycle arrest; cell fate commitment; cell-cell signaling; G2/M transition of mitotic cell cycle; lipid metabolic process; myoblast cell differentiation involved in skeletal muscle regeneration; negative regulation of epithelial cell proliferation; negative regulation of fat cell differentiation; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; organ morphogenesis; positive regulation of anagen; positive regulation of apoptosis; positive regulation of bone mineralization; positive regulation of cell proliferation; positive regulation of epithelial cell differentiation; positive regulation of ossification; positive regulation of osteoblast differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcriptional preinitiation complex assembly; protein stabilization; regulation of fat cell differentiation; regulation of proteasomal ubiquitin-dependent protein catabolic process; regulation of protein metabolic process; regulation of skeletal muscle development; regulation of transcription from RNA polymerase II promoter; sensory perception of taste; signal transduction; skeletal muscle fiber development; skeletal muscle regeneration; smoothened signaling pathway; Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin