Mouse Transient Receptor Potential Cation Channel Subfamily V Member 2 (TRPV2) ELISA Kit | TRPV2 elisa kit
Mouse Transient Receptor Potential Cation Channel Subfamily V Member 2 (TRPV2) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Background: TRPV2 encodes an ion channel that is activated by high temperatures above 52 degree C. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.TRPV2 is activated by high temperatures above 52 degree C. Alternatively it can be activated at lower temperatures by chemicals, such as the research tool 2-APB, the plant cannabinoid cannabidiol, and probenecid. It is blocked by ruthenium red and lanthanum. TRPV2 was independently discovered by two research groups and described in 1999. It was identified in the lab of David Julius as a close homolog of TRPV1, the first identified thermosensitive ion channel.
NCBI and Uniprot Product Information
Uniprot Description
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
Research Articles on TRPV2
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Product Notes
The Mouse TRPV2 trpv2 (Catalog #AAA9716663) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716663 ELISA Kit recognizes Mouse TRPV2. It is sometimes possible for the material contained within the vial of "Transient Receptor Potential Cation Channel Subfamily V Member 2 (TRPV2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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