Western Blot (WB)
(TRPV2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).)
Rabbit anti-Human TRPV2 Polyclonal Antibody | anti-TRPV2 antibody
TRPV2 Antibody (N-term)
Western Blot (WB)
(TRPV2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).)
Western Blot (WB)
(TRPV2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TRPV2 antibody detected the TRPV2 protein (arrow).)
temperatures above 52 degrees Celsius. The protein may be involved
in transduction of high-temperature heat responses in sensory
ganglia. It is thought that in other tissues the channel may be
activated by stimuli other than heat.
Nabissi, M., et al. Carcinogenesis 31(5):794-803(2010)
Monet, M., et al. Cancer Res. 70(3):1225-1235(2010)
Liu, G., et al. Cancer Genet. Cytogenet. 197(1):54-59(2010)
Saunders, C.I., et al. Biochim. Biophys. Acta 1792(10):1019-1026(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat. [provided by RefSeq, Jul 2008]
Uniprot Description
TRPV2: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: cell surface; integral to plasma membrane; melanosome; plasma membrane; endomembrane system
Molecular Function: calcium channel activity; ion transmembrane transporter activity; ion channel activity; cation channel activity
Biological Process: response to temperature stimulus; transport; response to heat; sensory perception; positive regulation of axon extension; transmembrane transport
Research Articles on TRPV2
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Product Notes
The TRPV2 trpv2 (Catalog #AAA9205052) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 52-81. The TRPV2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPV2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TRPV2 trpv2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPV2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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