Typical Testing Data/Standard Curve (for reference only)
Mouse Signal transducer CD24 ELISA Kit | Cd24 elisa kit
Mouse Signal transducer CD24 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
Uniprot Description
CD24: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. Genetic variations in CD24 are associated with susceptibility to multiple sclerosis (MS). A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological mechanism is regarded as an autoimmune attack of the myelin sheat, mediated by both cellular and humoral immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors influence susceptibility to the disease. Polymorphisms in CD24 may act as a genetic modifier for susceptibility and progression of MS in some populations, perhaps by affecting the efficiency of CD24 expression on the cell surface. Belongs to the CD24 family.
Protein type: Membrane protein, GPI anchor; Cell development/differentiation; Cell surface; Motility/polarity/chemotaxis
Cellular Component: anchored to external side of plasma membrane; cell surface; external side of plasma membrane; lipid raft; membrane; microvillus membrane; plasma membrane
Molecular Function: carbohydrate binding; protein binding; protein kinase binding; protein tyrosine kinase activator activity
Biological Process: apoptotic mitochondrial changes; apoptotic nuclear changes; cell activation; cell adhesion; cell migration; cell surface receptor linked signal transduction; chemokine receptor transport out of lipid raft; cholesterol homeostasis; elevation of cytosolic calcium ion concentration; heterophilic cell adhesion; homotypic cell-cell adhesion; leukocyte adhesion; leukocyte migration during inflammatory response; negative regulation of B cell proliferation; negative regulation of erythrocyte aggregation; negative regulation of erythrocyte clearance; negative regulation of neuroblast proliferation; negative regulation of neurogenesis; negative regulation of neuron differentiation; negative regulation of T cell homeostatic proliferation; negative regulation of transforming growth factor-beta3 production; neurite development; neuromuscular synaptic transmission; positive regulation of activated T cell proliferation; positive regulation of alpha-beta T cell proliferation; positive regulation of B cell apoptosis; positive regulation of calcium-mediated signaling; positive regulation of cell adhesion mediated by integrin; positive regulation of cell-cell adhesion; positive regulation of cell-cell adhesion mediated by integrin; positive regulation of inflammatory response to antigenic stimulus; positive regulation of integrin activation; positive regulation of MAP kinase activity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of T cell homeostatic proliferation; positive regulation of T cell mediated immune response to tumor cell; pre-B cell differentiation; regulation of B cell differentiation; regulation of cell-cell adhesion; regulation of cell-cell adhesion mediated by integrin; regulation of cytokine and chemokine mediated signaling pathway; regulation of MAPKKK cascade; regulation of phosphorylation; respiratory burst; response to estrogen stimulus; response to hypoxia; response to molecule of bacterial origin; synaptic vesicle endocytosis; T cell costimulation
Research Articles on Cd24
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Product Notes
The Mouse Cd24 cd24 (Catalog #AAA2885474) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885474 ELISA Kit recognizes Mouse Cd24. It is sometimes possible for the material contained within the vial of "Signal transducer CD24, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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