Typical Testing Data/Standard Curve (for reference only)
PGLYRP1/Pgrps elisa kit
Mouse PGLYRP1/Pgrps PicoKine ELISA Kit
Gene Names
Pglyrp1; PGRP; Tag7; Tasg7; PGRP-S; Pglyrp; Tnfsf3l
Reactivity
MouseThere is no detectable cross-reactivity with other relevant proteins.
Applications
ELISA
Synonyms
PGLYRP1/Pgrps; Mouse PGLYRP1/Pgrps PicoKine ELISA Kit; Peptidoglycan recognition protein 1; Cytokine tag7; Peptidoglycan recognition protein short; PGRP-S; Pglyrp1; Pglyrp; Pgrp; Pgrps; Tag7; PGLYRP1/Pgrps elisa kit
Reactivity
Mouse
There is no detectable cross-reactivity with other relevant proteins.
There is no detectable cross-reactivity with other relevant proteins.
Specificity
Natural and recombinant Mouse PGLYRP1/Pgrps
Sequence Length
182
Applicable Applications for PGLYRP1/Pgrps elisa kit
ELISA (EIA)
Assay Type
Quantitative Sandwich
Detection Range
15.6pg/ml-1000pg/ml
Sensitivity
<10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for PGLYRP1/Pgrps elisa kit
Principle of the Assay: Mouse PGLYRP1/Pgrps ELISA Kit was based on standard sandwich enzyme-linked immune- sorbent assay technology. A a monoclonal antibody from rat specific for PGLYRP1/Pgrps has been precoated onto 96-well plates. Standards(Expression system for standard: NSO, Immunogen sequence: F19-E182) and test samples are added to the wells, a biotinylated detection a biotinylated polyclonal antibody from goat specific for PGLYRP1/Pgrps is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Mouse PGLYRP1/Pgrps amount of sample captured in plate.
Background: Peptidoglycan recognition protein 1, also known as TAG7, is a protein that in humans is encoded by the PGLYRP1 gene. The PGLYRP1 gene is highly expressed in bone marrow, circulating Polymorphonuclear leukocytes (PMLs), and in the corneal epithelium. The PGLYRP1 protein is primarily found in the granules of PMLs. The PGLYRP1 protein plays an important role in the innate immune response. It is bactericidal against gram-positive bacteria such as S. aureus, S. epidermidis, and L. monocytogenes and generally has proinflammatory effects, inducing TNF-a and IFN-g in many tissues. PGLYRP-1 is also known to form a cytotoxic complex with HSP-70, suggesting it may also have a role in anti-cancer defense. As a pathogen recognition protein with antimicrobial properties, PGLYRP-1 is suspected to play an important role in maintaining the gut microbial flora.
Background: Peptidoglycan recognition protein 1, also known as TAG7, is a protein that in humans is encoded by the PGLYRP1 gene. The PGLYRP1 gene is highly expressed in bone marrow, circulating Polymorphonuclear leukocytes (PMLs), and in the corneal epithelium. The PGLYRP1 protein is primarily found in the granules of PMLs. The PGLYRP1 protein plays an important role in the innate immune response. It is bactericidal against gram-positive bacteria such as S. aureus, S. epidermidis, and L. monocytogenes and generally has proinflammatory effects, inducing TNF-a and IFN-g in many tissues. PGLYRP-1 is also known to form a cytotoxic complex with HSP-70, suggesting it may also have a role in anti-cancer defense. As a pathogen recognition protein with antimicrobial properties, PGLYRP-1 is suspected to play an important role in maintaining the gut microbial flora.
Product Categories/Family for PGLYRP1/Pgrps elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,489 Da
NCBI Official Full Name
peptidoglycan recognition protein 1
NCBI Official Synonym Full Names
peptidoglycan recognition protein 1
NCBI Official Symbol
Pglyrp1
NCBI Official Synonym Symbols
PGRP; Tag7; Tasg7; PGRP-S; Pglyrp; Tnfsf3l
NCBI Protein Information
peptidoglycan recognition protein 1
UniProt Protein Name
Peptidoglycan recognition protein 1
UniProt Gene Name
Pglyrp1
UniProt Synonym Gene Names
Pglyrp; Pgrp; Pgrps; Tag7; PGRP-S
Uniprot Description
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. May function in intracellular killing of bacteria. The soluble form triggers apoptosis in vitro.
Research Articles on PGLYRP1/Pgrps
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Product Notes
The Mouse There is no detectable cross-reactivity with other relevant proteins. PGLYRP1/Pgrps pglyrp1 (Catalog #AAA1751139) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1751139 ELISA Kit recognizes Mouse There is no detectable cross-reactivity with other relevant proteins. PGLYRP1/Pgrps. AAA Biotech's PGLYRP1/Pgrps can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PGLYRP1/Pgrps pglyrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGLYRP1/Pgrps, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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