Mouse Keratin 18 (KRT18) ELISA Kit | KRT18 elisa kit
Mouse Keratin 18 (KRT18) ELISA Kit
No significant cross-reactivity or interference between Keratin 18 (KRT18) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
NCBI and Uniprot Product Information
NCBI Description
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis.
Protein type: Nucleolus; Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: perinuclear region of cytoplasm; cytoplasm; keratin filament; nucleolus; microtubule organizing center; intermediate filament
Molecular Function: protein binding; structural molecule activity
Biological Process: anatomical structure morphogenesis; tumor necrosis factor-mediated signaling pathway; viral reproduction; intermediate filament cytoskeleton organization and biogenesis; cell cycle; negative regulation of apoptosis; Golgi to plasma membrane CFTR protein transport
Disease: Cirrhosis, Familial
Research Articles on KRT18
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Product Notes
The Mouse KRT18 krt18 (Catalog #AAA2024437) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2024437 ELISA Kit recognizes Mouse KRT18. It is sometimes possible for the material contained within the vial of "Keratin 18 (KRT18), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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