Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Delta-like protein 1 (DLL1) Standard Curve.)
Mouse Delta-Like Protein 1 (DLL1) ELISA Kit | DLL1 elisa kit
Mouse Delta-Like Protein 1 (DLL1) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Delta-like protein 1 (DLL1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Delta-like protein 1 (DLL1) Standard Curve.)
Background: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Sequence analysis predicted that the 723-amino acid DLL1 transmembrane protein, which is 88% identical to the mouse Dll1 protein, has a DSL domain followed by 8 tandem EGF-like repeats and a short cytoplasmic C-terminal region. Northern blot analysis revealed strongest expression of 4.0- and 4.6-kb transcripts in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver, and kidney. In situ hybridization analysis indicated upregulated expression of DLL1 in squamous cell carcinoma and in situ and invasive adenocarcinoma.
NCBI and Uniprot Product Information
Uniprot Description
DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: membrane; plasma membrane; integral to membrane; cytoplasmic vesicle
Molecular Function: protein binding; calcium ion binding; Notch binding
Biological Process: nervous system development; somitogenesis; Notch signaling pathway; inner ear morphogenesis; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; in utero embryonic development; multicellular organismal development; auditory receptor cell differentiation; odontogenesis of dentine-containing teeth; compartment specification; negative regulation of cell differentiation; somite specification; organ morphogenesis; negative regulation of neuron differentiation; regulation of neurogenesis; cell-cell signaling; negative regulation of auditory receptor cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cell communication; heart looping; determination of left/right symmetry; cell differentiation; auditory receptor cell fate commitment; inner ear development; positive regulation of Notch signaling pathway
Research Articles on DLL1
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Product Notes
The Mouse DLL1 dll1 (Catalog #AAA9717855) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9717855 ELISA Kit recognizes Mouse DLL1. It is sometimes possible for the material contained within the vial of "Delta-Like Protein 1 (DLL1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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