Typical Testing Data/Standard Curve (for reference only)
Mouse GAL9 (Galectin 9) CLIA Kit | GAL9 clia kit
Mouse GAL9 (Galectin 9) CLIA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This kit uses Sandwich-CLIA as the method. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to GAL9. Standards or samples are added to the appropriate micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for GAL9 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain GAL9, biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured spectrophotometrically by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of GAL9. You can calculate the concentration of GAL9 in the samples by comparing the RLU value of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: extracellular space; cytoplasm; intracellular; nucleus
Molecular Function: signal transducer activity; enzyme binding; galactose binding; carbohydrate binding
Biological Process: negative regulation of chemokine production; maternal process involved in pregnancy; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of activated T cell proliferation; negative regulation of natural killer cell mediated cytotoxicity; negative regulation of mast cell degranulation; positive regulation of NF-kappaB import into nucleus; response to lipopolysaccharide; female pregnancy; positive regulation of interleukin-1 beta secretion; negative regulation of tumor necrosis factor production; chemotaxis; signal transduction; activation of NF-kappaB transcription factor; positive regulation of interleukin-4 production; positive regulation of virion penetration into host cell; natural killer cell tolerance induction; negative regulation of interferon-gamma production; inflammatory response; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response
Research Articles on GAL9
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Product Notes
The Mouse GAL9 lgals9 (Catalog #AAA2530747) is a CLIA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2530747 CLIA Kit recognizes Mouse GAL9. It is sometimes possible for the material contained within the vial of "GAL9 (Galectin 9), CLIA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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