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Western Blot (WB) (All lanes : Anti-TUSC2 Antibody at 1:2000 dilutionLane 1: human heart lysateLane 2: human skeletal muscle lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Mouse anti-Human TUSC2 Monoclonal Antibody | anti-TUSC2 antibody

TUSC2 Antibody

Gene Names
TUSC2; PAP; FUS1; PDAP2; C3orf11
Reactivity
Human
Applications
Western Blot
Synonyms
TUSC2; Monoclonal Antibody; TUSC2 Antibody; Purified Mouse Monoclonal Antibody (Mab); Tumor suppressor candidate 2; Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2; C3orf11; FUS1; LGCC; PDAP2; anti-TUSC2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, k
Clone Number
1550CT388.74.12
Specificity
This TUSC2 antibody is generated from a mouse immunized with a recombinant protein of human TUSC2.
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Sequence Length
110
Applicable Applications for anti-TUSC2 antibody
Western Blot (WB)
Application Notes
WB ~~ 1:2000
Antigen Source
Human
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-TUSC2 Antibody at 1:2000 dilutionLane 1: human heart lysateLane 2: human skeletal muscle lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-TUSC2 Antibody at 1:2000 dilutionLane 1: human heart lysateLane 2: human skeletal muscle lysateLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 12 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-TUSC2 antibody
May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
Product Categories/Family for anti-TUSC2 antibody
References
Kondo M.,et al.Oncogene 20:6258-6262(2001). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Uno F.,et al.Cancer Res. 64:2969-2976(2004). Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
12074
NCBI Official Full Name
tumor suppressor candidate 2
NCBI Official Synonym Full Names
tumor suppressor candidate 2
NCBI Official Symbol
TUSC2
NCBI Official Synonym Symbols
PAP; FUS1; PDAP2; C3orf11
NCBI Protein Information
tumor suppressor candidate 2
UniProt Protein Name
Tumor suppressor candidate 2
UniProt Gene Name
TUSC2
UniProt Synonym Gene Names
C3orf11; FUS1; LGCC; PDAP2; Fus-1 protein
UniProt Entry Name
TUSC2_HUMAN

NCBI Description

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]

Uniprot Description

TUSC2: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. Belongs to the TUSC2 family.

Protein type: Tumor suppressor

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion

Molecular Function: protein binding

Biological Process: interleukin-15 production; cell proliferation; negative regulation of interleukin-17 production; cell-cell signaling; regulation of mitochondrial membrane potential; natural killer cell differentiation; response to defense-related host reactive oxygen species production; cell maturation; inflammatory response; cell cycle; phagocytosis; positive regulation of interleukin-10 production

Research Articles on TUSC2

Similar Products

Product Notes

The TUSC2 tusc2 (Catalog #AAA9215559) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TUSC2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TUSC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB ~~ 1:2000. Researchers should empirically determine the suitability of the TUSC2 tusc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TUSC2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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