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Immunohistochemistry (IHC) (Anti-SRR / Serine Racemase antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Mouse anti-Human SRR / Serine Racemase Monoclonal Antibody | anti-SRR antibody

Anti-SRR / Serine Racemase Antibody (clone 9E8) IHC-plus

Gene Names
SRR; ILV1; ISO1
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, Flow Cytometry, Functional Assay
Purity
Protein A/G purified
Synonyms
SRR / Serine Racemase; Monoclonal Antibody; Anti-SRR / Serine Racemase Antibody (clone 9E8) IHC-plus; Mouse Monoclonal [clone 9E8] (IgG1) to Human SRR / Serine Racemase; Human SRR / Serine Racemase; D-serine dehydratase; ISO1; L-serine ammonia-lyase; L-serine dehydratase; ILV1; Serine racemase; D-serine ammonia-lyase; anti-SRR antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9E8
Specificity
Human SRR / Serine Racemase
Purity/Purification
Protein A/G purified
Form/Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Concentration
0.86 mg/ml (varies by lot)
Sequence Length
340
Applicable Applications for anti-SRR antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Flow Cytometry (1:100)
IF (1:100)
IHC-P (1:5, 10 ug/ml)
WB (1:2000)
Immunogen
SRR / Serine Racemase antibody was raised against full length human recombinant protein of human SRR(NP_068766) produced in HEK293T cell.
Immunogen Description
Full length human recombinant protein of human SRR(NP_068766) produced in HEK293T cell.
Immunogen Type
Recombinant protein
Target Species
Human
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-SRR / Serine Racemase antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-SRR / Serine Racemase antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC)

(Anti-SRR / Serine Racemase antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-SRR / Serine Racemase antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunofluorescence (IF)

(Immunofluorescent staining of HepG2 cells using anti-SRR mouse monoclonal antibody.)

Immunofluorescence (IF) (Immunofluorescent staining of HepG2 cells using anti-SRR mouse monoclonal antibody.)

Immunofluorescence (IF)

(Anti-SRR mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SRR.)

Immunofluorescence (IF) (Anti-SRR mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SRR.)

Western Blot (WB)

(HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SRR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SRR.)

Western Blot (WB) (HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SRR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SRR.)

Flow Cytometry (FC/FACS)

(HEK293T cells transfected with either pCMV6-ENTRY SRR (Red) or empty vector control plasmid (Blue) were immunostained with anti-SRR mouse monoclonal, and then analyzed by flow cytometry.)

Flow Cytometry (FC/FACS) (HEK293T cells transfected with either pCMV6-ENTRY SRR (Red) or empty vector control plasmid (Blue) were immunostained with anti-SRR mouse monoclonal, and then analyzed by flow cytometry.)
Related Product Information for anti-SRR antibody
SRR Antibody, D-serine dehydratase Antibody, ISO1 Antibody, L-serine ammonia-lyase Antibody, L-serine dehydratase Antibody, ILV1 Antibody, Serine racemase Antibody, D-serine ammonia-lyase Antibody Description: Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,566 Da
NCBI Official Full Name
serine racemase isoform a
NCBI Official Synonym Full Names
serine racemase
NCBI Official Symbol
SRR
NCBI Official Synonym Symbols
ILV1; ISO1
NCBI Protein Information
serine racemase
UniProt Protein Name
Serine racemase
Protein Family
UniProt Gene Name
SRR
UniProt Entry Name
SRR_HUMAN

Uniprot Description

SRR: Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. Belongs to the serine/threonine dehydratase family.

Protein type: Amino Acid Metabolism - glycine, serine and threonine; EC 4.3.1.17; EC 5.1.1.18; EC 4.3.1.18; Isomerase

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: apical part of cell; cell soma; cytoplasm; plasma membrane

Molecular Function: ATP binding; calcium ion binding; D-serine ammonia-lyase activity; glycine binding; L-serine ammonia-lyase activity; magnesium ion binding; PDZ domain binding; protein homodimerization activity; pyridoxal phosphate binding; serine racemase activity; threonine racemase activity

Biological Process: aging; brain development; L-serine metabolic process; protein homotetramerization; pyruvate biosynthetic process; response to drug; response to lipopolysaccharide; response to morphine; serine family amino acid metabolic process

Research Articles on SRR

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Product Notes

The SRR srr (Catalog #AAA249432) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SRR / Serine Racemase Antibody (clone 9E8) IHC-plus reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRR / Serine Racemase can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC/FACS). Flow Cytometry (1:100) IF (1:100) IHC-P (1:5, 10 ug/ml) WB (1:2000). Researchers should empirically determine the suitability of the SRR srr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRR / Serine Racemase, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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