NCBI and Uniprot Product Information
Uniprot Description
SRR: Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. Belongs to the serine/threonine dehydratase family.
Protein type: EC 5.1.1.18; Isomerase; EC 4.3.1.18; Amino Acid Metabolism - glycine, serine and threonine; EC 4.3.1.17
Chromosomal Location of Human Ortholog: 17p13
Cellular Component: cell soma; apical part of cell; cytoplasm; plasma membrane
Molecular Function: protein homodimerization activity; glycine binding; threonine racemase activity; L-serine ammonia-lyase activity; magnesium ion binding; calcium ion binding; serine racemase activity; D-serine ammonia-lyase activity; ATP binding; PDZ domain binding; pyridoxal phosphate binding
Biological Process: response to drug; pyruvate biosynthetic process; L-serine metabolic process; response to morphine; response to lipopolysaccharide; brain development; serine family amino acid metabolic process; protein homotetramerization; aging