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Rabbit anti-Human SPINK4 Monoclonal Antibody | anti-SPINK4 antibody

Recombinant Anti-SPINK4 Antibody, Rabbit Monoclonal

Gene Names
SPINK4; PEC60; HEL136; PEC-60
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
SPINK4; Monoclonal Antibody; Recombinant Anti-SPINK4 Antibody; Rabbit Monoclonal; SPINK4 Antibody; Rabbit MAb; serine peptidase inhibitor; Kazal type 4; Anti-HEL136 Antibody; Anti-MGC133107 Antibody; Anti-PEC-60 Antibody; Anti-PEC60 Antibody; Anti-SPINK4 Antibody; anti-SPINK4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
265
Specificity
Human SPINK4
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SPINK4 antibody
ELISA (EIA) (Det)
Application Notes
ELISA (Det): This antibody will detect Human SPINK4 in ELISA pair set.
In a sandwich ELISA, it can be used as detection antibody when paired with.
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human SPINK4 Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human SPINK4 (rh SPINK4).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-SPINK4 antibody
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged infertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
References
Schneider, A. et al., 2004, Gastroenterol Clin North Am. 33 (4): 789-806. Wapenaar, MC. et al., 2007, Immunogenetics. 59 (5): 349-57. Brattsand, M. et al., 2009, J Invest Dermatol. 129 (7): 1656-65. Chen, T. et al., 2009, Proteins. 77 (1): 209-19. Noah, TK. et al., 2010, Exp Cell Res. 316 (3): 452-65.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,454 Da
NCBI Official Full Name
serine protease inhibitor Kazal-type 4
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kazal type 4
NCBI Official Symbol
SPINK4
NCBI Official Synonym Symbols
PEC60; HEL136; PEC-60
NCBI Protein Information
serine protease inhibitor Kazal-type 4; peptide PEC-60 homolog; gastrointestinal peptide; epididymis luminal protein 136; serine protease inhibitor, Kazal type 4
UniProt Protein Name
Serine protease inhibitor Kazal-type 4
Protein Family
UniProt Gene Name
SPINK4
UniProt Entry Name
ISK4_HUMAN

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Product Notes

The SPINK4 spink4 (Catalog #AAA8105593) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-SPINK4 Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPINK4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Det). ELISA (Det): This antibody will detect Human SPINK4 in ELISA pair set. In a sandwich ELISA, it can be used as detection antibody when paired with. Researchers should empirically determine the suitability of the SPINK4 spink4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPINK4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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